MELAS


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Related to MELAS: Merrf

MELAS

Acronym for mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. One of the mitochondrial disorders, this condition is usually hereditary, with a mutation at the mitochondrial genome at locus 3243.

MELAS

Mitochondrial Encephalomyopathy with Lactic Acidosis & Stroke-like episodes. A childhood condition associated with intermittent vomiting, proximal limb weakness and recurrent cerebral insults, resulting in hemiparesis, hemianopia or cortical blindness.
 
MELAS is due to an adenine-to-guanine substitution in a highly conserved portion of gene for tRNALeu(UUR), impairing the termination of mitochondrial transcription.

MELAS

Mitochondrial Encephalomyopathy with Lactic Acidosis & Stroke-like episodes Neurology A childhood condition, associated with intermittent vomiting, proximal limb weakness, and recurrent cerebral insults resulting in hemiparesis, hemianopia or cortical blindness. Cf MERRF.

MELAS

(mel'as)
Acronym for a constellation of findings that includes mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. One of the mitochondrial disorders, this condition is usually hereditary, with a mutation at the mitochondrial genome at locus 3243.
References in periodicals archive ?
Brit Asian rapper Raxstar lost his dad last weekend and has cancelled a number of his shows including the Mela.
The predominant feature of MELAS involves SEs, which commonly presents acute cortical blindness, psychiatric disorder, dementia, or paralysis.
For now, BIG MAGIC's talent show from the melas of Central India, Mele Ka BIG Star Season 3 will be conducting auditions at the Dargah Shariff Mela in Behraich on 29th and 30th June, 2013.
Besides Delhi, the melas are being held in Ghaziabad, Lucknow, Amritsar, Bangalore, Chennai and Hyderabad.
Our case suggests that carefully conducted neuraxial anaesthesia can be used safely in patients with MELAS syndrome, and that this technique can be considered as an option for similar patients undergoing lower limb procedures.
The Mela - which is free and open to all - has been running for 18 years in Newcastle and attracts around 30,000 people a year.
Historically, the different akharas have been highly competitive (to the point of warfare, as records from Kumbh Melas in Haridwar in the late 1700s show), (30) and while today hostility still exists between akharas, actual conflict is largely avoided, partially as a result of British intervention in the late-nineteenth century, which codified and set in stone the manner in which processions could be conducted.
The multicultural youth festival "L8 Mela" was organised by Liverpool Supplementary School with support from the Arabic Cultural Foundation.
"We have put young people at the heart of our mela by enabling our Youth Forum to play a part in the event organisation so that what we are offering is what young people really want on the day."
The Mela - or gathering - was organised by members of the Leamington and Warwick Mela Festival committee, with the aim of sharing Indian culture with other sections of the community.
THOUSANDS of people turned out for this weekend's mega Middlesbrough Mela 25.
Speaking on the occasion, a channel spokesperson said, "The first season received a great response from not only the melas but also our audiences.