MELAS


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Related to MELAS: Merrf

MELAS

Acronym for mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. One of the mitochondrial disorders, this condition is usually hereditary, with a mutation at the mitochondrial genome at locus 3243.

MELAS

Mitochondrial Encephalomyopathy with Lactic Acidosis & Stroke-like episodes. A childhood condition associated with intermittent vomiting, proximal limb weakness and recurrent cerebral insults, resulting in hemiparesis, hemianopia or cortical blindness.
 
MELAS is due to an adenine-to-guanine substitution in a highly conserved portion of gene for tRNALeu(UUR), impairing the termination of mitochondrial transcription.

MELAS

Mitochondrial Encephalomyopathy with Lactic Acidosis & Stroke-like episodes Neurology A childhood condition, associated with intermittent vomiting, proximal limb weakness, and recurrent cerebral insults resulting in hemiparesis, hemianopia or cortical blindness. Cf MERRF.

MELAS

(mel'as)
Acronym for a constellation of findings that includes mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. One of the mitochondrial disorders, this condition is usually hereditary, with a mutation at the mitochondrial genome at locus 3243.
References in periodicals archive ?
Brit Asian rapper Raxstar lost his dad last weekend and has cancelled a number of his shows including the Mela.
The predominant feature of MELAS involves SEs, which commonly presents acute cortical blindness, psychiatric disorder, dementia, or paralysis.
With Behraich being one of the most culturally rich cities in Uttar Pradesh, it leaves little doubt that the winner-hopefuls that will audition at the Dargah Shariff Mela will be some of the most-talented individuals from the region.
The next Kumbh Mela will take place in 2015 at Nashik, a city about 75 miles northeast of Mumbai.
Besides Delhi, the melas are being held in Ghaziabad, Lucknow, Amritsar, Bangalore, Chennai and Hyderabad.
Our case suggests that carefully conducted neuraxial anaesthesia can be used safely in patients with MELAS syndrome, and that this technique can be considered as an option for similar patients undergoing lower limb procedures.
The Mela - which is free and open to all - has been running for 18 years in Newcastle and attracts around 30,000 people a year.
Mela, a Sanskrit word meaning 'gathering', showcases a wide diversity of cultures, music, dance, arts, fashion and food.
22) The sadhus' militant identity was relegated to a ceremonial one, which only found expression in religious arenas such as the Kumbh Melas, where one can still see remnants of their militant past today.
Taking its name from a common South Asian word for "festival", the L8 Mela featured activities ranging from climbing walls, football skills, hand painting, bouncy castles, karate demonstrations, and competitions to traditional stalls.
MEMBERS of Coventry and Warwickshire's Indian community braved the miserable weather yesterday for the 11th annual Mela festival.