MEK6

MEK6

A MAPK kinase which activates p38 in vivo; it is highly expressed in skeletal muscle and regulates production of IL1 and TNF-alpha.
References in periodicals archive ?
Furthermore, p38[delta] MAPK coexpressed with either MEK6 or PKC[delta], both upstream p38 MAPK activators, elicited an apoptotic response similar to that induced by OA but in the absence of an external stimulus.
Eckert, "MEK6 regulates human involucrin gene expression via a p38[alpha]- and p38[delta]-dependent mechanism," Journal of Biological Chemistry, vol.