MEIS2

MEIS2

A gene on chromosome 15q14 that encodes Meis homeobox 2, a homeobox protein belonging to the three amino acid loop extension (TALE) family of homeodomain-containing proteins, which are highly conserved transcription regulators.
References in periodicals archive ?
MicroRNA204 decreased the expression of FOXC1 as well as its target genes: CLOCK, PLEKSHG5, ITG[beta]1, and MEIS2, indicating its involvement in the disease [38].
The early embryonic expression of Pax6 in the developing eye is autoregulated by Pax6 and, in addition, by other homeobox transcription factors such as Meis1 and Meis2 (Figure 4) [78].
MEIS1, which encodes a homeobox protein belonging to the TALE "three amino acid loop extension" family of homeodomain-containing proteins, as well as MEIS2 and PBX1 are found to have a critical function to suppress prostate cancer initiation and progression [21].