HDAC9(redirected from MEF-2 interacting transcription repressor (MITR) protein)
HDAC9A gene on chromosome 7q21.1 that encodes histone deacetylase 9, a protein with sequence homology to members of the histone deacetylase family and orthologous to Xenopus and mouse MITR genes, the protein product of which lacks a histone deacetylase catalytic domain. MITR represses myocyte enhancer factor-2 (MEF2) activity by recruiting multicomponent corepressor complexes—including CtBP and HDACs. HDAC9 may play a role in haematopoiesis.
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