CLEC5A

(redirected from MDL1)

CLEC5A

A gene on chromosome 7q33 that encodes a C-type lectin domain protein that regulates osteoclastogenesis and inflammation.

Molecular pathology
CLEC5A plays a central role in synovial and joint injury in autoimmune arthropathy.
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References in periodicals archive ?
miR125a targets the expression of Clec5a/ MDL1 which is required for granulocytic differentiation.
The molecular basis of myeloid malignancies
Accumulated unfolded proteins are processed by the ClpXP protein and transported across the inner mitochondrial membrane by the matrix ATP-dependent peptide transporter HAF-1 (Mdl1 in yeast) [147-149].
Langer, "Role of the ABC transporter Mdl1 in peptide export from mitochondria," Science, vol.
Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease
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