CLEC5A

(redirected from MDL1)

CLEC5A

A gene on chromosome 7q33 that encodes a C-type lectin domain protein that regulates osteoclastogenesis and inflammation.

Molecular pathology
CLEC5A plays a central role in synovial and joint injury in autoimmune arthropathy.
References in periodicals archive ?
miR125a targets the expression of Clec5a/ MDL1 which is required for granulocytic differentiation.
Accumulated unfolded proteins are processed by the ClpXP protein and transported across the inner mitochondrial membrane by the matrix ATP-dependent peptide transporter HAF-1 (Mdl1 in yeast) [147-149].
Langer, "Role of the ABC transporter Mdl1 in peptide export from mitochondria," Science, vol.