Also found in: Acronyms, Wikipedia.


Abbreviation for:
Doctor of Dental Medicine
major depressive disorder, see there
marijuana detection dog
mean daily dose
Medical Devices Directorate 
mine detection dog
minimum detected dose
multiple daily dosing
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Major depressive disorder, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


Abbrev. for Doctor of Dental Medicine.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Patient discussion about MDD

Q. What is MDD? I have heard this term on the radio referring to general depression, however I wanted to know what exactly is MDD.

A. A friend I made through this service refered me to the NIMH. They have a very nice website for the National Institute of Mental Health (NIMH) full of accurate descriptions of all the kinds of depression and other mental illnesses.

Under their Health and Outreach tab at:

Click on Depression which brings you to

and keep reading

Major depressive disorder, also called major depression, is characterized by a combination of symptoms that interfere with a person's ability to work, sleep, study, eat, and enjoy once–pleasurable activities. Major depression is disabling and prevents a person from functioning normally. An episode of major depression may occur only once in a person's lifetime, but more often, it recurs throughout a person's life.

Q. I like to know the signs of serious major depression in women? I am lecturer in a college who is very approachable to students. If you take the top 10 lectures in the college the students will vote me first. Though I am proud of it I am not jealous. One of the clubs chose me as the best lecturer of the year and wanted me to send to another country for a special training in their own expense. Now I am here in this training which lasts for 6 more months. First week I fell home sick without seeing my students and got depressed and moreover I could not CONCENTRATE in the training and COULD NOT SLEEP. I like to know the signs of serious major depression in women?

A. If I wish if I am a student then I like to get trained under you. I am jealous of your students. The symptoms of depression in women are the same as those for major depression.
Common complaints include:
• Depressed mood Loss of interest or pleasure in activities you used to enjoy
• Feelings of guilt, hopelessness and worthlessness
• Suicidal thoughts or recurrent thoughts of death
• Sleep disturbance (sleeping more or sleeping less)
• Appetite and weight changes
• Difficulty concentrating
• Lack of energy and fatigue

More discussions about MDD
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References in periodicals archive ?
The world's smartest and most sustainable fully built city district, MDD is described as Qatar's destination for living, leisure, and business, according to a statement on Sunday.
MDD is a common mental disorder characterized by a variety of symptoms -- including persistently depressed mood, loss of interest, low energy, insomnia or hypersomnia, and more.
MDD affects nearly 300 million people of all ages globally and is the leading cause of disability worldwide.
It can be extrapolated from the above that comorbid MDD in individuals with DM poses a significant public health issue.
A comparative cross-sectional study of inpatients and outpatients with MDD, bipolar I disorder (BID), and bipolar II disorder (BIID) who consulted psychiatry department of a tertiary care medical college between September 1st 2014 and September 1st 2015.
The rationale and design of this study have been described in detail elsewhere.[21] Briefly, patients with MDD were recruited from nine sites in China from December 2013 to December 2016.
This is a phase 2, multicenter, randomised, double-blind, placebo-controlled, 3-arm study to assess the safety, tolerability and efficacy of multiple oral doses of REL-1017 as adjunctive therapy in the treatment of MDD.
Also, the US Food and Drug Administration (FDA) approved vortioxetine (Trintellix) on 30 September 2013 for the treatment of MDD in adults.
The researchers observed a significant correlation for older age with a worse two-year MDD course for all four indicators (MDD diagnosis: odds ratio, 1.08; chronic symptom course: odds ratio, 1.24; time to remission: hazard ratio, 0.91; and depression severity change: regression coefficient, 1.06).
All patients were then followed for 2 or more years until the first appearance of MDD. The researchers also assessed baseline factors of age, sex, obesity, smoking status, alcohol use, comorbidities, and socioeconomic factors.
THE CHANCE OF DEVELOPING major depressive disorder (MDD) is much higher in patients who have acne, according to a retrospective cohort analysis published as a research letter.