ADAM1cda23

(redirected from MDC3)

ADAM1cda23

An ADAMs family protein encoded by ADAM23 on chromosome 2q33, which is highly expressed in the brain. It is essential for normal brain activity, possibly by serving as a ligand for binding proteins, and may play a role in cell-cell and cell-matrix interactions. Knock-out mice lacking expression of ADAM23 have ataxia, tremor and short life spans.
References in periodicals archive ?
In contrast, the MDC groups with greatest negative and positive effect on LOS are the Diseases and Disorders of the Ear, Nose, Mouth and Throat (MDC3) and the Mental Diseases and Disorders (MDC_19), respectively.
En ese mismo porcentaje de gilsonita y CA (G/ CA = 10%), las mezclas MDC-1, MDC-2 y MDC3 experimentan un incremento en su resistencia bajo carga monotonica (E/F) de 43,46%, 41,8% y 32,4%, respectivamente (ver la figura 3).