IL24

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IL24

A gene on chromosome 1q32 that encodes interleukin-24, a cytokine which may contribute to terminal cell differentiation. It has antiproliferative properties on melanoma cells. IL24 is also a popular, non-HUGO symbol for what is now designated IL17F, see there.
References in periodicals archive ?
Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR).
Other CB2 receptor-selective agonists MDA7, MDA19, JWH133, and LY2828360 were reported to prevent the development and suppress established paclitaxel-induced mechanical and cold allodynia [38, 42-46].
Xu et al., "MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models," British Journal of Pharmacology, vol.
In results published online in the Neurobiology Of Aging, the compound MDA7 was found to interact with receptors in the brain that play a role in the neuro-degenerative processes in Alzheimer's.
In the study, the compound MDA7 induced beneficial immune responses that limited the development of Alzheimer's disease.