Conclusion: The P-selectin and MCP1
values in the emergency department can differentiate sepsis patients according to the Q-SOFA criteria and showed 30-day mortality at a significant level.
Statins can partially refrain AT inflammation in obese mice , through the downregulation of mRNA MCP1
and IL6 expression  and also through inhibition of TLR4-induced expression of interferon-y in macrophages .
Curcumin antioxidant and anti-inflammatory effects seem to be linked to its hydroxyl and methoxy groups, whose functions end up giving a negative feedback in pro-inflammatory regulation of interleukins (IL-1,-2,-6,-8,-12) and cytokines (TNF-[alpha], MCP1
) of enzymes and genes of pro-inflammatory cytokines.
* Inflammation and oxidative stress drives production of monocyte chemoattractant protein-1 (MCP1
), recruiting monocytes and facilitating their penetration past the endothelium into the intima.
Jones, "Curcumin supplementation lowers TNF-[alpha], IL-6, IL-8, and MCP1
secretion in high glucose-treated cultured monocytes and blood levels of TNF-[alpha], IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats," Antioxidants and Redox Signaling, vol.
A study by Willing et al  revealed that the stromal cells secrete a variety of cytokines and differentiation factors, including monocyte chemoattractant protein-1 (MCP1
), osteoclast differentiation factor (ODF), and macrophage-colony stimulating factor (M-CSF).
Furthermore, EGCG attenuates TNF-[alpha]-induced production of monocyte chemotactic protein-1 (MCP1
) and reduces Akt phosphorylation (Ahn et al.
The increase of TNF-[alpha] and, to some extent, MCP1
levels in our patients is in concordance with the results obtained in patients with parthenium dermatitis  and trichloroethylene-induced hypersensitivity  and might be explained by the activities of activated T cells .
Furthermore, activation of this pathway may contribute to the establishment and progression of atherosclerosis by inducing the proliferation of arterial smooth muscle cells and increased synthesis and secretion of IL-8 and monocyte chemotactic protein (MCP1
showed that both high monocyte chemoattractant protein-1 (MCP1
) expression and high macrophage infiltration in prostate cancer specimens correlate with a high prostate-specific antigen (PSA) recurrence rate and that AT1R blockade (ARB) inhibits MCP-1 expression through the PI3K/Akt pathway and blocks macrophage infiltration in castration-resistant prostate cancer .
and Mcp2, two novel proteins involved in mitochondrial lipid homeostasis," Journal of Cell Science, vol.