MCL1


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MCL1

A gene on chromosome 11q21 that encodes an anti-apoptotic protein of the Bcl-2 family.
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However CCL1, MCL1 & IER-5 genes were reported to be significantly downregulated in BTB- infected cattle (24).
The protein is elevated in a variety of cancers, and a number of MCL1 inhibitors are in the cancer drug development pipeline worldwide.
It is important to note that these results do not demonstrate that miR-125b directly decreases the expression of BAK1, CASP2, MAP2K7, and MCL1 upon exposure to formaldehyde, nor that miR-142-3p directly increases the expression of ITGB8.
21] Human genes: BCL2, B-cell CLL/lymphoma 2; MCL1, myeloid cell leukemia sequence 1 (BCL2-related).