MCHR1

(redirected from MCH receptor 1)

MCHR1

A gene on chromosome 22q13.2 that encodes a G protein-coupled receptor and integral plasma membrane protein which binds melanin-concentrating hormone. MCHR1 can inhibit cAMP accumulation and stimulate intracellular calcium accumulation, and is probably involved in the neuronal regulation of food consumption.
References in periodicals archive ?
MCH is a 19-amino acid neuropeptide encoded by the Pmch gene and can bind to 2 G-protein-coupled receptors, the MCH receptor 1 (MCHR1) and MCH receptor 2 (MCHR2).