CCL2

(redirected from MCAF)
Also found in: Acronyms.

CCL2

A gene on chromosome 17q11.2-q21.1 that encodes a protein structurally related to the CXC subfamily of cytokines, which are characterised by two cysteines separated by a single amino acid. CCL2 is chemotactic for monocytes and basophils, but not neutrophils or eosinophils; it binds to chemokine receptors CCR2 and CCR4.

Molecular pathology
Altered expression of CCL2 has been linked to diseases characterised by monocytic infiltrates—e.g., psoriasis, rheumatoid arthritis, atherosclerosis.
References in periodicals archive ?
The relaxant effects of ACAF, MCPF, MCAF were shown to be mediated by [alpha] and [beta] adrenergic receptors in the ileum and colon, since tolazoline and propranolol blocked the relaxations.
Tickers featured: BALT, CA, CHKP, CSCO, ENTU, ISSX, MCAF, MSFT, RSAS, SYMC, VRSN.
The bio fertilizers will be sold to planters and vegetable growers at the MCAF retail outlets.