ADAM1baa10

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ADAM1baa10

A widely expressed member of the ADAMs family of proteins encoded by ADAM10 on chromosome 15q2|15q22.
Activity Controls proteolytic processing of Notch, mediates lateral inhibition in neurogenesis, cleaves pro-TNF-alpha, myelin basic protein, and type IV collagen. It is responsible for the proteolytic release of other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). ADAM 10 contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. ADAM 10 is inhibited by TIMP-1 and TIMP-3.
References in periodicals archive ?
According to the company, the MADM mobile anaesthesia delivery module is designed and manufactured at its ISO 13485-certified facility in Toronto, Ontario, Canada.
MIP is the same as the aggregation process traditionally mentioned in MADM and DVP is the decision process based on the aggregated global utility of each alternative.
(iii) first approach performing spectrum handoff using MADM in NEMO based CR vehicular networks.
(2018) Interval neutrosophic tangent similarity measure based MADM strategy and its application to MADM problems, Neutrosophic Sets and Systems, 19, 47-56.
In MADM approach, the testing data is classified based on the dissimilarity function applying the following detection rules.
One method of answering these questions is the Multi-Attribute Decision Model (MADM).
The Complex Proportional Assessment (COPRAS) method as a new method of MADM was suggested by Zavadskas et al.
Section 2 presents the related work on MADM methods and assessment of indoor environment.
Keywords: the trapezoid fuzzy linguistic variables (TFLVs), the TFLHHA operator, multiple attribute decision making (MADM)
The technique Zong and his team used was Mosaic Analysis with Double Markers (MADM), developed for studying developmental biology and modeling diseases in mice.