MAPK6

MAPK6

A gene on chromosome 15q21 that encodes a Ser/Thr protein kinase, which is closely related to the MAP kinases. MAP kinases integrate multiple biochemical signals and are involved in cell proliferation, differentiation, transcription, regulation and development. MAPK6 localises in the nucleus and is activated in fibroblasts in response to treatment by serum and phorbol esters.
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Probe set ID Gene symbol Control G418 ATSE 7983763 MAPK6 233 314 382 8046380 ITGA6 216 323 385 8051670 SOS1 291 386 520 8084963 PAK2 173 252 360 8090162 ITGB5 330 357 220 8111915 SEPP1 3337 2847 1761 Probe set ID 1/2(G418 + ATSE) ATSE/control 7983763 405 1.64 8046380 220 1.78 8051670 515 1.79 8084963 338 2.08 8090162 150 -1.50 8111915 1131 -1.87 G418 (0.45 mg/mL); ATSE: Akebia trifoliate seed extract (0.625 mg/mL); 1/2(G418 + ATSE): a combination of half dose of each accordingly.
Transcript levels of MAPK6 were higher in liver, while those of MAPK12 were higher in mammary tissues.