MAP2K2(redirected from MAPK/ERK kinase 2)
MAP2K2A gene on chromosome 19p13.3 that encodes mitogen-activated protein kinase kinase 2, which catalyses the simultaneous phosphorylation of a threonine and a tyrosine residue in MAP kinases; it also activates the ERK1 and ERK2 MAP kinases.
Defects of MAP2K2 cause cardiofaciocutaneous syndrome.
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