MAP2C | definition of MAP2C by Medical dictionary
MAP2 (redirected from MAP2C)
MAP2 A gene on chromosome 2q34 that encodes a protein belonging to the microtubule-associated protein family, which are involved in microtubule assembly, an essential step in neurogenesis. Based on similar genes in rodents, in humans the MAP2 protein product may play a role in determining and stabilising dentritic shape during neuronal development.
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References in periodicals archive
DNA from reference samples was amplified at the following 8 microsatellite loci: NVHRT21, BM1225, BM4516, FCB193, MAP2C
, RT5, RT9, and RT30 (Wilson et al.
Mandelkow, "Phosphorylation of MAP2c
and MAP4 by MARK kinases leads to the destabilization of microtubules in cells," Cell Motility and the Cytoskeleton, vol.
Tambien se ha observado un incremento en la fosforilacion de Tau y MAP2c
, junto con la presencia PHF, en cultivos primarios de neuronas corticales de seres humanos y ratas tratados con [beta]A.