MAOI


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.
Related to MAOI: SSRI, Moai, MAOI diet

inhibitor

 [in-hib´ĭ-tor]
1. any substance that interferes with a chemical reaction, growth, or other biologic activity.
2. a chemical substance that inhibits or checks the action of a tissue organizer or the growth of microorganisms.
3. an effector that reduces the catalytic activity of an enzyme.
ACE i's (angiotensin-converting enzyme i's) see angiotensin-converting enzyme inhibitors.
angiogenesis inhibitor a group of drugs that prevent growth of new blood vessels into a solid tumor.
aromatase i's a class of drugs that inhibit aromatase activity and thus block production of estrogens; used to treat breast cancer and endometriosis.
C1 inhibitor (C1 INH) a member of the serpin group, an inhibitor of C1, the initial component activated in the classical complement pathway. Deficiency of or defect in the protein causes hereditary angioedema.
carbonic anhydrase inhibitor an agent that inhibits the enzyme carbonic anhydrase; used in treatment of glaucoma and sometimes for epilepsy, familial periodic paralysis, acute mountain sickness, and kidney stones of uric acid.
cholinesterase inhibitor anticholinesterase.
COX-2 i's (cyclooxygenase-2 i's) a group of nonsteroidal antiinflammatory drugs that act by inhibiting cyclooxygenase-2 activity; they have fewer gastrointestinal side effects than other NSAIDs. Two members of the group are celecoxib and rofecoxib.
gastric acid pump inhibitor an agent that inhibits gastric acid secretion by blocking the action of H+,K+-ATPase at the secretory surface of gastric parietal cells; called also proton pump i.
HIV protease inhibitor any of a group of antiretroviral drugs active against the human immunodeficiency virus; they prevent protease-mediated cleavage of viral polyproteins, causing production of immature viral particles that are noninfective. Examples include indinavir sulfate, nelfinavir mesylate, ritonavir, and saquinavir.
HMG-CoA reductase i's a group of drugs that competitively inhibit the enzyme that catalyzes the rate-limiting step in cholesterol biosynthesis, and are used to lower plasma lipoprotein levels in the treatment of hyperlipoproteinemia. Called also statins.
membrane inhibitor of reactive lysis (MIRL) protectin.
monoamine oxidase inhibitor any of a group of drugs that inhibit the action of monoamine oxidase, the enzyme that breaks down norepinephrine and serotonin, prescribed for their antidepressant action; the most widely used ones are isocarboxazid, phenelzine, and tranylcypromine. They are also used in the prevention of migraine.
α2-plasmin inhibitor α2-antiplasmin.
plasminogen activator inhibitor (PAI) any of several regulators of the fibrinolytic system that act by binding to and inhibiting free plasminogen activator. Their concentration in plasma is normally low, but is altered in some disturbances of bodily hemostasis. PAI-1 is an important fast-reacting inhibitor of t-plasminogen activator and u-plasminogen activator. Its synthesis, activity, and release are highly regulated; elevated levels of it have been described in a number of disease states. PAI-2 is a normally minor inhibitor that greatly increases in concentration during pregnancy and in certain disorders. PAI-3 is protein C inhibitor.
platelet inhibitor any of a group of agents that inhibit the clotting activity of platelets; the most common ones are aspirin and dipyridamole. See also antiplatelet therapy.
protease inhibitor
1. a substance that blocks activity of endopeptidase (protease), such as in a virus.
protein C inhibitor the primary inhibitor of activated anticoagulant protein C; it is a glycoprotein of the serpin family of proteinase inhibitors and also inhibits several other proteins involved in coagulation (thrombin, kallikrein, and coagulation factors X and XI) and urokinase. Called also plasminogen activator inhibitor 3.
proton pump inhibitor gastric acid pump i.
reverse transcriptase inhibitor a substance that blocks activity of the reverse transcriptase of a retrovirus and is used as an antiretroviral agent. Some are nucleosides or nucleoside analogues, and those that are not are therefore often called non-nucleoside reverse transcriptase inhibitors.
selective serotonin reuptake inhibitor (SSRI) any of a group of drugs that inhibit the inactivation of serotonin by blocking its absorption in the central nervous system; used as antidepressants and in the treatment of obsessive-compulsive disorder and panic disorder.
serine protease inhibitor (serine proteinase inhibitor) serpin.
topoisomerase i's a class of antineoplastic agents that interfere with the arrangement of DNA in cells.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

MAOI

Abbreviation for monoamine oxidase inhibitor.
Farlex Partner Medical Dictionary © Farlex 2012

MAOI

abbr.
monoamine oxidase inhibitor
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

MAOI

Monoamine oxidase inhibitor(s). A family of therapeutic drugs (e.g., phenelzine) which are used to treat atypical depression or when tricyclic antidepressants fail. MAOIs have traditionally been relegated to a secondary role in treating depression (tricyclic antidepressants and SSRIs have better therapeutic profiles) given their tendency towards inducing hypertensive crises when MAOI-treated patients ingest tyramine-containing products (e.g., aged cheese or wine). MAOIs may be more effective when depression is accompanied by anxiety.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

MAOI

Monoamine oxidase inhibitor A family of therapeutic drugs–eg, phenelzine, that are used to treat atypical depression or when tricyclic antidepressants fail; MAOIs have traditionally been relegated to a 2º role in treating depression, given their tendency towards inducing hypertensive crises when MAOI-treated Pts ingest tyramine-containing products; MAOIs may be most effective when depression is accompanied by anxiety
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

MAOI

Abbreviation for monoamine oxidase inhibitor.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

MAOI

See MONOAMINE OXIDASE INHIBITOR.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Monoamine oxidase inhibitor (MAOI)

An older class of antidepressants.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

MAOI

Abbreviation for monoamine oxidase inhibitor.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
The differential diagnosis of the serotonin syndrome in turn includes malignant neuroleptic syndrome (MNS), MAOI overdose, tyramine reaction, strychnine ingestion, and the use of cocaine, amphetamines or other sympathomimetic drugs.
In its lowest strength, Emsam can be used without the dietary restrictions (described below) that are needed for all oral MAOIs approved for treating major depression.
Key: UK (United Kingdom); USA (United States of America); SSRI (selective serotonin reuptake inhibitor); MAOI (monoamine oxidase inhibitor)
Recently, supplement manufacturer Alternative Health Research, Inc., settled a case involving the death of a 20-year-old college student who took "Ultimate Xphoria Herbal Supplement." It contained ephedra and had inadequate warnings about the product's use with an MAOI. The young man died from cardiac arrhythmia.(25)
As in the case of the high-potency benzodiazepines and imipramine, treatment with phenelzine or another MAOI generally lasts 6 months to a year.
Caffeine use renders more toxic or less effective monoamine oxidase inhibitors (MAOI) and lithium salts used to treat some mood disorders (Neil, Himmelhock, Mallinger, Mallinger, & Hanin, 1978).
Additionally, Adhansia XR is contraindicated in patients with a known hypersensitivity to methylphenidate or product components, as well as patients receiving concurrent treatment with a monoamine oxidase inhibitor or who have used an MAOI within the preceding 14 days.
Apart from gracing the Kimalel auction where he bought 1,000 goats at Sh10 million, Ruto also opened Maoi abattoir and Mogotio tannery to aide slaughter and grading of livestock products.
Astute clinicians will recognize that antidepressants that lack 5HT reuptake (eg, bupropion, mirtazapine) are not on this list of agents that may increase SS risk when taken with an MAOI. Older papers often list mirtazapine, but as a 5HT2 A antagonist, it does not possess a plausible mechanism by which it can induce 5HT toxicity.
Do not combine DLPA with MAOI drugs like Anipryl, used to treat Cushing's Disease and canine cognitive dysfunction, or amitraz, an ingredient in tick collars.
We asked innovation advocate Maoi Arroyo, who teaches at AIM while managing her four businesses, what sectors or industry subsectors that were likely to thrive in a unified Asean economy.
* Concurrent use with monoamine oxidase inhibitors (MAOI) or use within 14 days of MAOI use (2.2, 4.1, 5.2, 7.3)