MAGI1 | definition of MAGI1 by Medical dictionary
MAGI1 A gene on chromosome 3p14.1 that encodes a putative scaffolding protein at cell–cell junctions, which may regulate acid-induced ACCN3 currents by modulating cell surface expression.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive
Qu et al., "MAGI1
inhibits migration and invasion via blocking MAPK/ERK signaling pathway in gastric cancer," Chinese Journal of Cancer Research, vol.
Jiang, "Regulation and involvement in cancer and pathological conditions of MAGI1
, a tight junction protein," Anticancer Research, vol.
recruits Dll1 to cadherin-based adherens junctions and stabilizes it on the cell surface.