ADAM1bja19

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ADAM1bja19

An ADAMs family protein encoded by ADAM19 on chromosome 5q33.3, which is involved in various physiologic and pathological processes, including cell migration, cell adhesion, cell-cell and cell-matrix interactions, signal transduction, and organogenesis.
Normal activity ADAM19 is involved in proteolytic processing of neuregulins involved in neurogenesis and synaptogenesis, suggesting glial cell regulation. ADAM19 cleaves alpha-2 macroglobulin, and may have a role in bone formation. ADAM19 is highly expressed in dorsal root ganglia and ventral horns of the spinal cord, where peripheral neuronal cell lines differentiate. Like ADAM17, but to a lesser degree, ADAM19, can function as a TNF-alpha sheddase, releasing TNF-alpha from a membrane-bound precursor. ADAM19 is also involved in cardiac morphogenesis, giving rise to the membranous septa and valves. Knock-out mice lacking ADAM19 have ventricular septal defects and underdeveloped valves; most die shortly after birth, which may be due to the loss of proteolytic regulation of ErbB ligands by ADAM19.
References in periodicals archive ?
Earlier on Sunday morning, the police wing of Abu Dhabi Police rescued an Emirati motorist who was involved in a collision on the Al Maddam - Al Shuwaib Road in Al Ain.
Contract Award for: Construction of road from kasalong college gate to maddam para paka road of Baghaichari upazilla under CHTDB, Rangamati.
The foure strangers seeke for you maddam to take theyr leaue: and there is a fore-runner come from a fift, the Prince of Moroco, who brings word the Prince his Maister will be heere to night.
Home address: All of Maddam Merun Loa, Barua Para, Ward No.7 Fetekhar Kul, Ramu P.s, District- Cox's Bazaar.
Just yards down the seafront are two more must see attractions - The Sealife Centre and Maddam Tussaud's, which has none of the queuing problems of its London equivalent.
Maddam's Ranch: The site of a five-acre farm in the 1890s that specialized in fruit.
4 The property acquired by the queen was 'one messuage and one yarde lande called the Pole with thappurtenances lyeing and beinge in longney aforesaid and one Acre of meadowe lying in maddam and one Acre and one Rodd of lande lying in the Southefeild and the third parte of one pasture called Agasmeade als Brethermeade lying and being in Longhey aforesaid late in the tenure and occupacion of one Elizabeth Spicer widdowe deceased parcell of the Copiehold and Customary landes of the said mannor of Longhey and demised and demisable by Coppy of Courte Rolle of the said mannor'.
Maddam, pray give mee leave without flatterie to tell your Ladyship that you do not onlie excell those of your owne sexe but allso the most able and learned of the other; and therefore I conceive that expression of yours (viz that as a woman you are altogether unable and unfitt to undergoe the care of the estate left to your sister's children) is onlie inserted out of the modestie of your nature; for (pardon mee) if I can possibly understand itt otherwise.
Maddam, you have bereft me of all words, onely my blood speakes to you in my vaines, and there is such confusion in my powers, as after some oration fairely spoke by a beloved Prince, there doth appeare among the buzzing pleased multitude.
A total of 195 candidates, including 43 women, are competing for seats spread across Kalba, Khorfakkan, Dhaid, Dibba Al Hisn, Bataeh, Maliha, Hamriya, and Maddam in an election that is being held under the slogan of 'Take Part in Decision Making,' following the directives of His Highness Dr.
Contractor address : Uttor Maddam Halishahr, P.O: Anandabazar-4215, Chittagong Port, Chittagong City Corporation Chittagong