MAD2L1

(redirected from MAD2)
Also found in: Acronyms, Wikipedia.

MAD2L1

A gene on chromosome 4q27 that encodes a component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate, and which may recruit MAD2L1 to unattached kinetochores. MAD2L1 is required for the execution of the mitotic checkpoint, which monitors kinetochore-spindle attachment and inhibits the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Mentioned in ?
References in periodicals archive ?
MAD2 is secured by a long term lease and is designed to offer up to 1.
For the full 2009, AWB achieved net profit of MAD2.
Manual of Archival Description [6] (en sus dos versiones, MAD, 1986 y MAD2, 1989) producto de la colaboracion entre la Society of Archivists y la British Library, que luego fue desarrollada por la Universidad de Liverpool, usada por los archiveros britanicos.
MAD2 will be constructed in two phases, each phase providing 800 square metres of equipped space and over 1.