MAD2L1

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MAD2L1

A gene on chromosome 4q27 that encodes a component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate, and which may recruit MAD2L1 to unattached kinetochores. MAD2L1 is required for the execution of the mitotic checkpoint, which monitors kinetochore-spindle attachment and inhibits the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
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The MAD2 trading card set depicts selected MAD Magazine cover art from the past 40 years on the front of each card.
The MAD2 data centre is adjacent to Interxion's MAD1 data centre in the heart of Madrid's "Silicon Alley" and will offer customers the same rich connectivity options as MAD1, which houses over 70 carriers, the broadest connectivity in Spain.
Packages of MAD and MAD2 trading cards are being sold nationwide.