CD59(redirected from MACIF)
Also found in: Acronyms.
a glycosylphosphatidylinositol-anchored membrane protein present on many hemopoietic cells, vascular endothelium, epithelial cells, and placenta that inhibits membrane complement attack and may be involved in T-cell signal transduction; absent or defective in paroxysmal nocturnal hemoglobinuria.
Farlex Partner Medical Dictionary © Farlex 2012
CD59A 65-kD membrane, glycosyl-phosphatidylinositol-anchored complement-neutralising protein encoded by CD59 on chromosome 11p13, which inhibits the complement membrane attack complex, binding to C8 and C9 during assembly of the complex.
Most leukocytes and red cells.
May be absent in some forms of paroxysmal nocturnal haemoglobinuria.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.