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Ernst, scientist in Hapsburg Empire, 1838-1916. See: Mach band, Mach number.


A gene on chromosome 2q33-q34 that encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family which, once activated by proteolytic processing, plays a central role in the execution phase of cell apoptosis, as well as various stages of embryological development. CASP8 is an initiator-type caspase, which is activated by, and interacts with, upstream adaptor molecules through CARD and DED protein–protein interaction domains; it is involved in the programmed cell death induced by Fas and various apoptotic stimuli. It is highly expressed in peripheral blood leukocytes and in the spleen, thymus and liver.

Molecular pathology
CASP8 has been detected in the insoluble fraction of affected brain regions in Huntington disease, suggesting a role in neurodegenerative diseases.
References in periodicals archive ?
Model 8 is an asymmetric model indicating that high Mach scores in combination with loosely structured organizations results in high sales performance.
Gender and the interaction term for Mach by age are not significant statistically.
Contrary to the position that high MACH's contribute to productivity is Hunt and Chonko's research (1984) which found no correlation between success and high Machiavellianism.
Proposition 8: High MACH salespeople will have lower sales performance ratings on overall selfratings.
The independent variable of Machiavellianism was measured using Christie and Geis's (1970) Mach V scale (for a detailed analysis of the MACH scales see Vleeming 1979).
A paired T-test with mach and age revealed a correlation that was negative.
Table 3 indicates that the cell means for the 281 samples show a higher mean for high mach than low mach in both retail and industrial selling.
Table 2 reveals that the two independent variables Mach and Self-Monitoring have a strong interaction effect.
The results indicate a preliminary findings of the higher the Mach level and the sales levels the lower the self-ratings.