MACF1

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MACF1

A gene on chromosome 1p32-p31 that encodes F-actin-binding protein, which is thought to play a role in cross-linking actin to other cytoskeletal proteins and to microtubules. MACF1 plays a key role in ERBB2-dependent stabilisation of microtubules at the cell membrane, it upregulates the Wnt-receptor signalling pathway, and it is involved in translocating AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. It has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics.

MACF1 may deliver transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. It also plays a key role in wound healing and epidermal cell migration; it is required for efficient upward migration of bulge cells in response to tissue trauma, which reflects its ability to co-ordinate microtubule dynamics and polarise hair follicle stem cells.
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All of the Candidates for the MACF Awards of Excellence were nominated from the local manufacturing community, with the exception of the President's Award and Outstanding Contributors, which was chosen by Ken Brace, the MACF Board President.
Grapefruit seeds were obtained from grapefruits (Citrus paradisi Macf.), variety Red.
The allegations surround August's trip to the national cadet camp in Crowborough, Sussex, attended by around 400 young recruits from MACF, which has 34 detachments across Merseyside.
La efectividad del tipo de estacion cebo MS2[R] y el atrayente Cera Trap[R] respecto a otros atrayentes alimenticios y estaciones cebo artesanales fueron estudiadas en la Comunidad Canadas, Municipio Martinez de la Torre, estado de Veracruz, Mexico, en toronja (Citrus paradisi Macf).
In the follow-up evaluation, participants underwent a clinical interview, completed a questionnaire on their progress, had a follow-up brain SPECT scan, and retook the MACF.
Therefore, MACF's purpose is twofold: to properly and effectively treat SED, abused, and neglected children, and subsequently to reduce the long-term costs associated with these children growing up to become adults who may require extensive services.
f., (Rutanaceae) Zanthoxylum elephantiasis Macf. (Rutaceae) and Zanthoxylum martinicensis (Lam.) DC.
Hill, APIACEAE) Pimenton, pimiento (Capsicum annuum L., C M V SOLANACEAE) Pomelo (Citrus paradisi Macf., RUTACEAE) C M Poroto haba (Canavalia gladiata (Jacq.) C M DC., FABACEAE) Poroto moradito, overito, rosadito, blanco, negro guillador (Phaseolus C V vulgaris L.
(5.) See, for example., Ian MacF. Ragers, Canadian Law of Planning and Zoning (Toronto: Carawell, 1973-2000) (looseleaf), sec.