MAC25 | definition of MAC25 by Medical dictionary
IGFBP7 (redirected from MAC25)
IGFBP7 A gene on chromosome 4q12 that encodes a member of the insulin-like growth factor binding protein (IGFBP) family which that insulin-like growth factors I and II and circulates in the plasma. IGFBP7 stimulates prostacyclin production and cell adhesion.
A variant of IGFBP7 has been associated with retinal arterial macroaneurysm.
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References in periodicals archive
Li et al., "Down-regulation of T1A12/ mac25
, a novel insulin-like growth factor binding protein related gene, is associated with disease progression in breast carcinomas," Oncogene, vol.
A follistatin-like gene, mac25
, may act as a growth suppressor of osteosarcoma cells.
One should also note that both of the studies cited determined DARC and mac25
as novel markers for high ECs.