MAB


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MAB

Abbreviation for monoclonal antibody.

monoclonal antibody

Diagnostics
Mabs are used in diagnostics by radioactively labelling them to target malignant cells, detect metastases and screen body fluids for microorganisms, or measure levels of circulating hormones.

Fringe oncology
Alternative healthcare providers may include therapeutic Mabs as a part of treatment.

Immunology
A highly specific antibody formed by a clone of B lymphocytes, either naturally (e.g., in cold haemagglutinin) or produced synthetically by fusing an immortal cell (mouse myeloma) to a cell producing an antibody against a desired antigen.

Oncology
Mabs are increasingly used in cancer management as they directly inhibit the growth of certain tumours, can be chemically bound to toxins that are lethal to malignant cells, stimulate the complement system in destroying malignant cells, can be used to purge the BM of malignant cells, and form the basis for vaccines and drug delivery systems.
 
Adverse effects
Allergic reactions, fevers, chills, hypotension, liver and kidney problems.
 
Pathology
Mabs are used in pathology to differentiate tumour subtypes with batteries of Mabs raised against intermediate filaments or membrane antigens.

MAB

Monoclonal antibody, Monoclonal antibodies

mAb

abbrev. MONOCLONAL ANTIBODY.
References in periodicals archive ?
Ismail opined that MAB should be monitored by the Prime Minister Office or Ministry of Finance and reduce Khazanah's stake as the sole shareholder in the airline to eliminate any "internal noises."
However, Many said that Mab did not run illicit sawmill operations.
In Sharjah, MAB works closely with Shurooq across all of the emirate's museums, the Al Qasba area and Al Majaz waterfront.
For MAB count, the criteria consisted of [less than or equal to]50,000 CFU/mL as a quality premium payment, [greater than or equal to]50,000 to <100,000 CFU/mL for minimum payment, and [greater than or equal to]100,000 CFU/mL for milk not suitable for processing at the industrial level in accordance with the requirements established in Regulation no.
And the AHR to methacholine was significantly decreased with the treatment of anti-IL-5 mAb (P < 0.05) and ABPS (P < 0.05), or the combined treatment group (P < 0.01) (Figure 1).
After the initial batch of MABs was built, improvements were introduced.
mAbs. P3 mAb (IgM, k) recognizes NeuGc-containing gangliosides and sulfated glycolipids [1].
The hybridoma clone of a murine anti-BMP-2 mAb was expanded and used in order to generate chimeric anti-BMP-2 mAb according to procedures described by Ansari et al.
The Kuala Lumpur High Court ruling is likely to come as a relief for relatives, many of whom had feared they would not be able to get compensation from Malaysia Airlines Systems (MAS) after it transferred all its assets and operations to MAB in a restructuring exercise last year.
LITERATURE Wales has announced award-winning performance poet, writer and promoter Mab Jones has won the contract to deliver the second International Dylan Thomas Day in 2016.
The scope of the scheme involves building the Crude Distillation Unit MAB Unit 111, Atmospheric Residue Desulphurisation (ARDS) Unit MAB Units 112/212, Hydrocracker Unit (HCR) MAB Unit 114 & MAB Unit 214, Diesel Hydrotreating (DHT) Unit MAB Unit 116 & MAB Unit 216, Continuous Catalytic Reformer (CCR) MAB Unit 127, Naphtha Hydrotreater (NHT) Unit (23500 BPSD) MAB Units 117, Underground Piping MAB Unit 179, Vacuum Rerun (VR) Unit MAB Unit 213 and DHT Flare MAB Unit 249.
Laboratories characterizing monoclonal antibodies (mAb) now have additional hydrophobic interaction chromatography (HIC) selectivity options, thanks to the expanded family of Thermo Scientific MAbPac HIC HPLC columns.