MAB


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MAB

Abbreviation for monoclonal antibody.

MAB

abbreviation for monoclonal antibody.

monoclonal antibody

Diagnostics
Mabs are used in diagnostics by radioactively labelling them to target malignant cells, detect metastases and screen body fluids for microorganisms, or measure levels of circulating hormones.

Fringe oncology
Alternative healthcare providers may include therapeutic Mabs as a part of treatment.

Immunology
A highly specific antibody formed by a clone of B lymphocytes, either naturally (e.g., in cold haemagglutinin) or produced synthetically by fusing an immortal cell (mouse myeloma) to a cell producing an antibody against a desired antigen.

Oncology
Mabs are increasingly used in cancer management as they directly inhibit the growth of certain tumours, can be chemically bound to toxins that are lethal to malignant cells, stimulate the complement system in destroying malignant cells, can be used to purge the BM of malignant cells, and form the basis for vaccines and drug delivery systems.
 
Adverse effects
Allergic reactions, fevers, chills, hypotension, liver and kidney problems.
 
Pathology
Mabs are used in pathology to differentiate tumour subtypes with batteries of Mabs raised against intermediate filaments or membrane antigens.

MAB

Monoclonal antibody, Monoclonal antibodies

mAb

abbrev. MONOCLONAL ANTIBODY.

MAb

monoclonal antibody.
References in periodicals archive ?
MAB FM has managed a healthy development of its business since it began operations in 2005, experiencing double digit year-to-date growth.
Investigacion y Desarrollo: la salida al MAB puede incrementar las inversiones en investigacion y desarrollo (I + D); pero aquellas empresas que ya tienen inversiones en I + D, se muestran renuentes a salir a bolsa porque pierden esa informacion confidencial (Pagano, Panetta y Zingales, 1998; Farinos y Sanchis, 2009).
The isotype of 2F9-C9 mAb was then determined according to the ELISA method described above.
Attracted by the enlarging Chinese market foreign Mab producers try to introduce their Mab products into China.
En la historia del desnudo en las artes visuales, MAB tiene lugar de honor.
En Dario, Mab primero aparece en El velo de la reina Mab y La copa de las hadas (ambos en 1887).
Novo Nordisk will initiate a Phase I trial with IL-21 mAb in 2010.
The MAB program offers the support and flexibility needed, allowing professionals in the food and agriculture industry to complete the course according to their own personal schedule, taking advantages of technologies such as the Internet and downloadable podcasts.
This CD40 antagonistic mAb is an antibody which binds to CD40 expressed on antigen-presenting cell (APC).
The assays using proMBP-reactive antibodies, such as the ones using mAb A1 as capture and any of mAbs B5, B6, and A11 as tracer, or the assays using any of mAbs A8, A9, and A16 as capture and mAb A1 as tracer, were able to detect PAPP-A in pregnancy (Fig.
We've learned so much about OvaRex MAb, but we now need to confirm these observations with new clinical data,'' said Dr.
MAB is valued on a par with its peers but this does not appear justified by its relative growth prospects.