According to the French-American-British Cooperative Group (BENNETT et al., 1976) and the World Health Organization (McMANUS, 0005), acute erythroid leukemia is classified as a form of acute myeloid leukemia (AML M6) and subdivided into two clinical presentation forms: AML M6A, more often described in humans, and AML M6B
, more commonly reported in animals (VALLI et al., 2002).
The first TVM with antiapoptotic activity whose expression was examined is glycoprotein M6B
Type of X-ray equipment and film processor at each hospital Names X-ray unit Installation Processor Installation year year Hospital Philips RO 1992 Kodak 2002 1 1230 Rotarix x-oMAT M6B
Hospital Shimadzu 1986 Kodak 2007 2 Rad/Flo x-oMAT Circlex 5000 RA Hospital Siemens 1982 Fujifilm 2004 3 0946004G444G FPM3800AD Hospital Shimadzu 2005 Kodak 2007 4 Radiotex x-oMAT 000 RA A calibration validation was done on the Harshaw 4500 TLD system (Erlangen, Germany) used to read the TLD cards for patient dose.
Although the FAB classification has not been formally updated since its 1985 revision, other investigators modified the FAB classification informally by expanding the M6 category to include M6a and M6b
In the recent World Health Organization (WHO) classification, AML-M6 is included under AML not otherwise categorized with two subtypes: erythroleukemia (M6a) and pure erythroid leukemia (M6b
The protein (sea squirt DM-3), derived from eight exons, was related to M6B
protein in its N-terminal half (residues 9-195 of 441 amino acids).
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