GPM6B

(redirected from M6B)

GPM6B

A gene on chromosome Xp22.2 that encodes a multipass membrane protein of the myelin proteolipid protein family involved in: regulating osteoblast function and bone formation; matrix vesicle release by osteoblasts and maintenance of the actin cytoskeleton; cellular trafficking of SERT; and in regulating serotonin uptake. It may be involved in neural differentiation,
References in periodicals archive ?
1976) and the World Health Organization (McMANUS, 0005), acute erythroid leukemia is classified as a form of acute myeloid leukemia (AML M6) and subdivided into two clinical presentation forms: AML M6A, more often described in humans, and AML M6B, more commonly reported in animals (VALLI et al.
The main objective of this note is to describe a case of acute erythroid leukemia with erythroid predominance (AML M6B, "erythremic mielosis") in a horse, unprecedented in the literature, with emphasis on the anatomopathological aspects.
After the definitive diagnosis of AML M6B for bone marrow cytology, the owner elected euthanasia and the filly was sent to the pathology laboratory for postmortem examination.
Type of X-ray equipment and film processor at each hospital Names X-ray unit Installation Processor Installation year year Hospital Philips RO 1992 Kodak 2002 1 1230 Rotarix x-oMAT M6B Hospital Shimadzu 1986 Kodak 2007 2 Rad/Flo x-oMAT Circlex 5000 RA Hospital Siemens 1982 Fujifilm 2004 3 0946004G444G FPM3800AD Hospital Shimadzu 2005 Kodak 2007 4 Radiotex x-oMAT 000 RA
The protein (sea squirt DM-3), derived from eight exons, was related to M6B protein in its N-terminal half (residues 9-195 of 441 amino acids).
Consistent with this observation, neighbor-joining phylogenetic trees (not shown) indicate that sea squirt DM-1 and DM-2 are more similar to M6A proteins than they are to M6B or DM20.
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