GPM6A

(redirected from M6A)

GPM6A

A gene on chromosome 4q34 that encodes a multipass membrane protein involved in neuronal differentiation, migration of neuronal stem cells, neuronal plasticity, filopodia motility and probably synapse formation. It may be involved in neuronal NGF-dependent Ca2+ influx, regulating endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), and in enhancing internalisation and recycling of mu-type opioid receptors.
References in periodicals archive ?
1976) and the World Health Organization (McMANUS, 0005), acute erythroid leukemia is classified as a form of acute myeloid leukemia (AML M6) and subdivided into two clinical presentation forms: AML M6A, more often described in humans, and AML M6B, more commonly reported in animals (VALLI et al.
Jack Barkin, 960 Lawrence Ave West, Suite 404, Toronto, ON M6A 3B5; j.
Address correspondence to Kelsey Simons, Baycrest, Kunin-Lunenfeld Applied and Evaluative Research Unit, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada; e-mail: ksimons@klaru-baycrest.
specialist teacher of the blind, Toronto District School Board Vision Program, Vision Program, 38 Orfus Road, Room 158, Toronto, Ontario, M6A 1L6, Canada; e-mail: <robin.
Memorial donations may be made to the Dorothy Heitin Memorial Fund, c/o the Benjamin Foundation, 3429 Bathurst Street, Toronto, M6A 2C3, 416-780-0324
Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, ON M6A 2E1 (Canada).
Toronto, ON M6A 2EI, Canada (e-mail: jryan@rotman-baycrest.
Consistent with this observation, neighbor-joining phylogenetic trees (not shown) indicate that sea squirt DM-1 and DM-2 are more similar to M6A proteins than they are to M6B or DM20.
Toronto, ON M6A 2T2, Canada; 416-783-4140; khan@khanscope.
Toronto, ON M6A 2T2, Canada; 416-783-4140, fax: 416-783-7697; khan@khanscope.
coordinator, Vision Program, Toronto District School Board, 38 Orfus Road, Room 158, Toronto, Ontario, M6A 1L6, Canada; e-mail: <carol.
Simons, PhD, MSW, is a social work scientist, Baycrest Centre for Geriatric Care, Kunin-Lunenfeld Applied Research Unit, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada; e-mail: ksimons@klaru-baycrest.