M4Eo

M4Eo

acute myelomonocytic leukemia with abnormal eosinophils.
References in periodicals archive ?
51,69) Unlike AML M4Eo, where granules are enlarged, the granules in chronic eosinophilic leukemia associated with FIP1L1-PDGFRA are commonly small and sparse (Figure 2, A and B).
Schnittger S, Bacher U, Haterlach C, Kern W and Haferlach T, Rare CBFB-MYH11 fusion transcripts in AML with inv(16)/t(16;16) are associated with therapy-related AML M4eo, atypical cytomorphology, atypical immunophenotype, atypical additional chromosomal rearrangements and low white blood cell count: a study on 162 patients Leukemia 2007;21:725-31.
Two patients had AL (one type B, common; and one biphenotypic), and 105 had acute myeloid leukemia: 1 with French-American-British subtype Mo, 11 with subtype M1, 13 with subtype M2, 65 with subtype M3, 4 with subtype M4, 2 with subtype M4Eo, 5 with subtype M5, 2 with subtype M6, 1 who was not classified, and 1 with subtype M1 at relapse.
Patients with t(8; 21) frequently present with the French-American-British (FAB) morphologic subtype M2 or acute myeloid leukemia with differentiation, while patients with inv(16) more often are diagnosed with FAB subtype M4Eo or acute myelomonocytic leukemia with eosinophilia.