FAB classification

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FAB classification

 
(French-American-British) a classification of acute leukemia produced by a three-nation joint collaboration; acute lymphoblastic leukemia is subdivided into three types and acute myelogenous leukemia is subdivided into eight types.
French-American-British (FAB) classification of acute leukemias: the myeloid leukemias are divided into eight types (M0-7) and the lymphoblastic leukemias into three (L1-3). From Hoffbrand and Pettit, 2000.

FAB classification

French-American-British classification of acute leukemias based on the study of microscopic features and cytochemistry of blast cells; it subdivides acute myelogenous leukemias into 8 groups (M0-M7) and acute lymphoblastic leukemias into 3 groups (L1-L3); widely used in clinical practice.

FAB classification

French-American-British classification of acute leukemia Hematology A schema that divides acute leukemias into lymphoid–ALL or myeloid–AML cell lines; of childhood ALL, 70% are predominantly L1, 27% are L2, and 3% or less are L3 or Burkitt cell type, in adults with ALL, 30% are L1, 65% are L2, and 5% are L3
FAB classification, acute leukemias
Acute lymphocytic leukemia (ALL)
L1  Small monotonous lymphocytes
L2  Mixed L1- and L3-type lymphocytes
L3  Large homogeneous blast cells
Acute myeloid leukemia (AML)
M1  Myeloblasts without maturation
M2  Myeloblasts with maturation (best AML prognosis)
M3  Hypergranular promyelocytic leukemia (faggot cells)
M3V  Variant, microgranular promyelocytic leukemia
M4  Myelomonocytic leukocytes
M5  Monocytic, subtype
  a. Poorly differentiated monocytic leukemia
  b. Well differentiated monocytic leukemia
M6  Erythroleukemia/DiGuglielmo syndrome
M7  Megakaryocytic leukemia Pleomorphic undifferentiated cells with cytoplasmic blebs; myelofibrosis or ↑ BM reticulin; positive for platelet peroxidase antifactor VIII
References in periodicals archive ?
y/Sex locytes, % 1 28/M 36 M3 BM 2 81/F 73 M3 BM 3 63/M 87 M3v PB 4 66/M 87 M3 PB 5 56/F 58 M3 BM 6 34/M 80 M3v PB 7 43/M 64 M3 BM 8 43/F 91 M3v BM 9 37/F 55 M3 BM Abbreviations: BM, bone marrow; FAB, French-American-British classification; FISH, fluorescence in situ hybridization; M3, classic hypergranular type of APL; M3v, microgranular variant type of APL; PB, peripheral blood; RT-PCR, reverse transcription-polymerase chain reaction; WBC, white blood cells.
Alternatively, the gods and planets who come to preside may stay on the first gallery, taking their places, "as they are in height" (M3v), and converting the theater to a two-tier Hell; they need only then retire from the gallery.
The witch Erichtho in Sophonisba may have seemed just as preposterous to him (M3v).