Myeloid differentiation factor 88 (MyD88) is the key members of TLR pathway, and it transfers the antigen signature to trigger a series of signaling cascades that culminate in transcription of numerous downstream genes such as inflammatory cytokines, chemokines, interferons, lymphokine
, and complement factors [51, 52].
Some of these defector molecules, migration inhibition factor (MIF) a lymphokine
, inhibit the migration of macrophages in the same culture medium .
were thought to have significant therapeutic potential.
Shifts in interleukin-4 and interferon-gamma production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines
on spontaneous IgE synthesis.
Biological properties and clinical use of calf thymus extract TFX-Polfa, in Goldstein A L (ed): Thymic Hormones and Lymphokines
Interactions of neuropeptides and lymphokines
. In: Scharrer B, Smith EM, Stefano GB, editors.
Interferons, a group of multiple lymphokines
. Springer Semin Immunopathol.
There are several different types of cytokines such as monokines (cytokines produced by monocytes and macrophages), lymphokines
(cytokines produced by lymphocytes), inflammatory peptides (cytokines produced by neutrophils), and vasoactive amines (cytokines produced by platelets and mast cells).
, monokines, and other polypeptides that regulate immunologic, inflammatory, and reparative host responses.
Helper T-cells produce powerful chemicals, called lymphokines
, that mobilize other immune system substances and cells.
Korbet cites the presence of a circulating permeability factor such as lymphokines
or cytokines as possible culprits in idiopathic disease.
Uromodulin (Tamm-Horsfall glycoprotein): a renal ligand for lymphokines
. Science 1987;237:1479-84.