lymphokine-activated killer cells


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Related to lymphokine-activated killer cells: LAK cells, Natural killer cells

lymphokine-activated killer cells

LAK cells, see there.

lymphokine-activated killer cells

Cells artificially produced by incubating lymphocytes from cancer patients with INTERLEUKIN-2 (IL-2). The result is a class of natural-killer cells whose targets are not restricted to cells carrying particular antigens. They offer potential as treatment modalities.
References in periodicals archive ?
Rosenberg, "Lymphokine-activated killer cell phenomenon.
Nevertheless, it has been shown that CB-derived NK and lymphokine-activated killer cells are able to lyse non-cultured fresh leukemia blasts, readily respond to IL-2 and IL-12, and mediate relatively high levels of apoptosis-mediated cytotoxicity against target cell lines (18), (19).
A lymphokine, previously designed interleukin T and produced by a human adult T cell leukemia line, stimulates T cell proliferation and the induction of lymphokine-activated killer cells. Proc.