Rye Staging System

(redirected from Lymphocytic predominant)

Rye Staging System

A system for staging Hodgkin's disease delineated in 1966, which divided it into 4 distinct clinicopathological categories, based on data provided by the then popular method of lymphangiography. Cf Ann Arbor classification, Cotswolds classification.
Rye Classification–Hodgkin's disease
Lymphocytic predominant 10% of cases, more common in young adult ♂, usually early/low-stage disease without 'B' symptoms, 5-year survival: 90%
Nodular sclerosing 40%; more common in young adult ♀, usually early and low-stage disease with or without 'B' symptoms, 5-year survival: 70%
Mixed cellularity 40%; more common in young adult ♂, often stage II-III disease with or without 'B' symptoms, 5-year survival: 50%
Lymphocyte-depleted 10%; more common in older adult ?, usually stage III-IV disease with or without 'B' symptoms, 5-year survival, 30%
References in periodicals archive ?
The most often reported is the epithelial membrane antigen (EMA), which is expressed in Hodgkin disease, mainly nodular lymphocytic predominant Hodgkin disease type (12) and plasma cell neoplasms.
The anterior mediastinal mass was diagnosed as thymoma, lymphocytic predominant type.

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