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disease of the lymph nodes; called also adenopathy.
angioimmunoblastic lymphadenopathy (angioimmunoblastic lymphadenopathy with dysproteinemia (AILD)) a systemic disorder resembling lymphoma characterized by fever, night sweats, weight loss, generalized lymphadenopathy, hepatosplenomegaly, macropapular rash, polyclonal hypergammaglobulinemia, and Coombs'-positive hemolytic anemia. It is considered to be a nonmalignant hyperimmune reaction to chronic antigenic stimulation; there is proliferation of B cells accompanied by profound deficiency of T cells. The disease follows a progressive but extremely variable course: some patients survive for a long period without chemotherapy; in other patients, overwhelming infections rapidly lead to death
dermatopathic lymphadenopathy regional lymph node enlargement associated with melanoderma and other dermatoses marked by chronic erythroderma.
immunoblastic lymphadenopathy angioimmunoblastic lymphadenopathy.
lymphadenopathy syndrome a condition occurring in immunocompromised individuals, characterized by unexplained lymphadenopathy for 3 or more months that involves extrainguinal sites, which on biopsy reveal nonspecific lymphoid hyperplasia. See also AIDS-related complex.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


1. Any disease process affecting a lymph node or lymph nodes.
2. The appearance of enlarged lymph nodes found on a radiologic examination of any kind.
[lymphadeno- + G. pathos, suffering]
Farlex Partner Medical Dictionary © Farlex 2012


(lĭm-făd′n-ŏp′ə-thē, lĭm′fə-dn-)
n. pl. lymphadenopa·thies
An enlargement of the lymph nodes, usually associated with disease.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


A generic term for lymph node enlargement of any aetiology, benign or malignant.

Lymphadenopathy, aetiology
• Viral—Infectious mononucleosis, CMV, HIV.
• Bacterial—Typhoid, TB, syphilis, Yersinia.
• Lymphoproliferative—especially lymphoma
• Metastases.

Lipid storage, Niemann-Pick, sphingomyelia.

Phenytoin, allopurinol, isoniazid.

Automimmune, rheumatoid arthritis, sarcoid, GVHD.

Benign hyperplasia, Langerhans cell histiocytosis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Enlarged lymph nodes, follicular hypertrophy, swollen lymph glands Hematology Enlargement of lymph nodes of any etiology; the differential diagnostic considerations are multiple and divided into reactive patterns; benign lymphadenopathy is characterized by
1. Variability of the follicle–germinal center size;.
2. Lack of capsular or fat invasion;.
3. Mitotic activity confined to the germinal center;.
4. Cortical localization and inhomogeneous distribution of the follicles. See Angiography lymphadenopathy, Benign lymphadenopathy, Dermatopathic lymphadenopathy, Phenytoin lymphadenopathy, Shotty lymphadenopathy.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


Any disease process affecting a lymph node or lymph nodes.
[G. lympha spring water +aden gland + G. pathos, suffering]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


(lim″fad″ĕ-nop′ă-thē) [ lymph- + adenopathy]
Enlarge picture
CERVICAL LYMPHADENOPATHY: Squamous cell carcinoma of the neck
Enlargement of lymph nodes (LN), typically to greater than 1.5 cm. The increased size is caused by activation and proliferation of lymphocytes and phagocytic white blood cells within the node or by invasion of the node by tumor. Most often, lymphadenopathy is found in nodes involved in local, regional, or systemic infections; it results occasionally from cancers. Lymphadenopathy may also be found in an array of other, less common illnesses, including thyroiditis, thyrotoxicosis, autoimmune diseases (e.g., rheumatoid arthritis), sarcoidosis, and drug reactions (e.g., phenytoin). See: illustration

Enlarged LNs may be tender or not; tenderness often is present when lymph nodes swell rapidly (e.g., in response to infections, hypersensitivity reactions, or some fulminant lymphomas). Rock-hard, enlarged, and immobile LNs are typical of metastatic cancer, whereas rubbery LNs are found in lymphomas. LNs that do not resolve spontaneously within 4 to 6 weeks, or for which no obvious explanation exists, usually are sampled by biopsy or aspiration.

dermatopathic lymphadenopathy

Widespread lymphadenopathy secondary to various skin disorders.
See: table
CategoryExamplesLocationAge of patientTextureSizeAssociated signs or symptomsDiagnostic testsNecessity for biopsy or aspirate
Bacterial infectionStrep throat; cat scratch diseaseAngle of the jaw; axilla, neckChild or preteen; anyRelatively soft and tender; relatively soft and tender1 sq. cm; > 1 cmFever, sore throat, tonsillar exudate, malaise, headache, difficulty swallowing; may have fever, night sweats, weight lossCan be diagnosed clinically; antibody blood testsNo; not usually
GranulomaTuberculosis; sarcoidosisNeck, chest; hilum of the lung and other locationsAny; usually adultsRelatively soft and tender; rubbery> 1 cm; > 1 cm, sometimes massiveMay have fever, night sweats, weight loss, productive sputum; cough, shortness of breath, may have systemic illness, or be asymptomaticTuberculin (purified protein derivative), interferon blood test, sputum for acid-fast bacilli; blood for ACE levelsOccasionally; often
Metastatic cancerBreast cancerAxilla next to the breastAdultsStoneEspecially likely if > 2 cmLump in the breastMammography, ultrasound, other imaging techniquesYes
LymphomaHodgkin lymphomaChest, neck, axilla, groin, or all of these Young adultRubbery> 1 cmMay have fever, night sweats, weight loss, enlarged spleenRadiologic imagingYes
Viral infectionMononucleosis; HIV/AIDSHead and neck, spleen; generalizedYoung adult; any, but most often young adult or adultRubbery; firmAbout 1 cm; variableMay have fever, night sweats, weight loss; fever, night sweats, weight loss, or symptoms of opportunistic infectionTests for Epstein-Barr virus, heterophile antibody; antibody blood testsNo; not usually
Medical Dictionary, © 2009 Farlex and Partners


Any disease process affecting a LYMPH NODE. Also known as lymphadenosis.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


An enlargement of a lymph gland. The preauricular lymph node located 1 cm in front of the external ear drains the orbital region and is sometimes involved with eyelid and conjunctival infection (e.g. adult inclusion conjunctivitis, follicular conjunctivitis). Syn. adenopathy (although strictly speaking this term refers to the enlargement of any gland).
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann


1. Any disease process affecting lymph nodes.
2. The appearance of enlarged lymph nodes found on x-rays.
[G. lympha spring water + aden gland + G. pathos, suffering]
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about lymphadenopathy

Q. my friend ate a bar of chocolate and now her left neck gland is swollen any ideas why? no other symptoms

A. it can be an infection -just like brandon said- or although this is rare, it can also be an allergic reaction.
if it is an infection, you can usually find such other infection symptoms like : fever, pain in that swollen area, increased white blood cells (in blood work test), etc.

if it is an allergy, usually it will fade away itself in couple of days, or you can just try to consume anti-allergic drugs, such as : loratadine and maybe combined with dexamethasone.

Good luck, and stay healthy always..

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References in periodicals archive ?
* Filariasis as a rare cause of isolated lymph node enlargement has been described.
In conclusion, bilateral pulmonary involvement, pulmonary involvement of all lobes, and lymph node enlargement were significantly more frequent CT findings in TB patients with DM compared with non-diabetic TB patients.
In our setting tuberculous lymphadenitis/HIV-related lymphadenopathy remains a relatively common cause for lymph node enlargement and can very often reliably be diagnosed by FNA.
Histological examination confirmed the tubercular origin of the lymph node enlargement, with no gallbladder stones or other disease that could give an alternative explanation for the fistula.
Manifestations of CSD are well described and include self-limited course of fever along with lymph node enlargement linked epidemiologically with a history of intimate contact with cat, mainly scratch or bite.
Itching is the commonest symptom, caused by bites that may become infected with Staphylococcus aureus, with localised lymph node enlargement. Examination can help to confirm the diagnosis--black specks (louse faeces) might be visible, as might bite marks on the scalp and nits attached to the hair shaft.
ATHE presence of acne is commonly associated with lymph node enlargement in this area.
CT and MRI scans showed a thin paravertebral abscess with some osteomyelitis of the ninth dorsal vertebral body and upper abdominal lymph node enlargement. Polymerase chain reaction of aspirate from the mass demonstrated the presence of Bartonella henselae, the investigators said (Clin.
This might explain the high number of cases presenting with single lymph node enlargement.
Six months later, CT enterography showed multiple thickening of the small intestine wall, and the descending and sigmoid colon, along with multiple air sacs, lumen stenosis, celiac lymph node enlargement, and small intestine incomplete torsion.
Generalized lymphadenopathy involves lymph node enlargement in more than one region of the body.

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