lyase

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Related to Lyases: Isomerases, Transferases

lyase

 [li´ās]
any of a class of enzymes that remove groups from their substrates (other than by hydrolysis), leaving double bonds, or that conversely add groups to double bonds.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ly·ase

(lī'ās),
Class name for those enzymes removing groups nonhydrolytically (EC class 4); prefixes such as "hydro-" and "ammonia-" are used to indicate the type of reaction. Trivial names for lyases include synthases, decarboxylases, aldolases, and dehydratases. Compare: synthase, synthetase.
Farlex Partner Medical Dictionary © Farlex 2012

lyase

(lī′ās′)
n.
Any of a group of enzymes that catalyze the cleavage of bonds without hydrolysis or oxidation, often resulting in a new double bond or ring structure, or that catalyze the addition of chemical groups to double bonds.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

ly·ase

(lī'ās)
Class name for enzymes removing groups nonhydrolytically (EC class 4); prefixes such as "hydro-," and "ammonia-" are used to indicate the type of reaction. Trivial names for lyases include synthases, decarboxylases, aldolases, dehydratases.
Compare: synthase, synthetase
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

lyase

an enzyme that catalyses
  1. the addition of groups to double bonds,
  2. the removal of groups to form double bonds.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Capitani, "Identifying key residues of sphinganine-1phosphate lyase for function in vivo and in vitro," Journal of Biological Chemistry, vol.
Igarashi, "Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol," Biochemical and Biophysical Research Communications, vol.
The enzymes hydroxymethylglutaryl-CoA reductase, type III geranylgeranyl diphosphate synthase, phosphomevalonate kinase, hydroxymethylglutaryl-CoA synthase, prenylcysteine oxidase/farnesylcysteine lyase, and protein farnesyltransferase subunit beta are each coded by two copies of the genes.
Our results revealed that, among the tested fungi, Penicillium echinulatum and Trichoderma hamatum showed the highest pectolytic activity for both pectinases enzymes, pectin methyl esterase (PME) and pectin lyase (PL).
Sherwood, "Pectin lyase and polygalacturonase production by Rhizoctonia solani and other fungi," Phytopathology Journal, vol.
Polyphenol Oxidase, Peroxidase, Phenylalanine Ammonia Lyase and Tyrosine Ammonia Lyase Specific Activity.
The endoxanthanase cleaving the backbone linkage of the xanthan has been purified [8], whereas the xanthan lyase was not characterized and the way to modify the terminal side chains of xanthan remained unclear.
from soil samples of Damascus, and then focus on optimizing the production and enzymatic characterization of extracellular pectin lyase by Bacillus subtilis strain RSY7.
O-acetylserine (thiol) lyase [OAS-TL; EC 4.2.99.8] catalyzes the formation of cysteine from O-acetylserine (OAS) and hydrogen sulfide with the release of acetic acid.
The disaccharide products formed by the action of the chondroitin ABC lyase or chondroitin AC lyase on urinary CS were identified by strong-anion-exchange HPLC, as reported elsewhere (35-37).
Cytosolic S1P formed by SphK1 may also act on some recently identified intracellular targets for its involvement in inflammatory signaling pathways before being broken down by S1P lyase. These intracellular targets include TNF receptor-associated factor 2 (TRAF2, an E3 ubiquitin ligase that is a key component of the NF[kappa]B pathway [50]; apoptosis inhibitor cIAP2, an E3 ubiquitin ligase that is a key component of the IRF-1 (interferon-regulatory factor 1-) mediated immune and sterile inflammation) [51].