luteal phase defect


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lu·te·al phase de·fect

a condition characterized by inadequate secretion of progesterone during the luteal phase of the menstrual cycle, with resultant infertility; subnormal luteal function commonly attributed to abnormal pituitary gonadotropin secretion and ovarian follicle dysfunction.

luteal phase defect

Gynecology A deficiency–seen in 3 to 5% of infertile women and cause of ± 1/3 of recurent early spontaneous abortions–in the amount of progesterone produced—or the length of time produced, which translates into an inability of the endometrium to support pregnancy. See Corpus luteum.

lu·te·al phase de·fect

(lū'tē-ăl fāz dē'fekt)
Condition characterized by inadequate secretion of progesterone during the luteal phase of the menstrual cycle, with resultant infertility.
Synonym(s): luteal phase deficiency.

luteal phase defect

A deficiency in either the amount or the duration of postovulatory progesterone secretion by the corpus luteum. Insufficient hormonal stimulation results in inadequate preparation of the endometrium for successful implantation and support of the growing embryo. This condition is associated with infertility or habitual spontaneous first-trimester abortion.
See: menstrual cycle
See also: defect
References in periodicals archive ?
The luteal phase defect. Fertil Steril 1976; 27(4):351-6.
Women should not be offered an endometrial biopsy to evaluate the luteal phase because there is no evidence that medical treatment of luteal phase defect improves pregnancy rates.
Luteal phase defect in habitual abortion: progesterone in saliva.