interstitial lung disease

(redirected from Lung fibrosis)

interstitial lung disease (ILD)

a respiratory disorder characterized by a dry, unproductive cough and dyspnea on exertion. The patient may have swallowing disorders or joint and muscle pain and a history of industrial exposure to inorganic dusts, such as asbestos or silica. X-ray films usually show fibrotic infiltrates in the lung tissue, usually in the lower lobes. The fibrosing or scarring of lung tissue is often the result of an immune reaction to an inhaled substance. However, interstitial lung disease may result from viral, bacterial, or other infections; uremic pneumonitis; cancer; a congenital or inherited disorder; or circulatory impairment. The condition may be self-limiting, progress to respiratory or cardiac failure, or undergo spontaneous recovery.

interstitial lung disease

Diffuse interstitial pulmonary fibrosis Pulmonology A group of disorders characterized by scarring of deep lung tissue, leading to SOB and loss of functional alveoli, limiting O2 exchange; ILD is more common in smokers Etiology Inorganic and organic dusts, gases, fumes, vapors, medications, radiation, and certain lung infections, hypersensitivity pneumonitis, coal worker's pneumoconiosis, silicosis, byssinosis, idiopathic

Interstitial lung disease

About 180 diseases fall into this category of breathing disorders. Injury or foreign substances in the lungs (such as asbestos fibers) as well as infections, cancers, or inherited disorders may cause the diseases. They can lead to breathing or heart failure.
Mentioned in: Chest X Ray
References in periodicals archive ?
Because SSc-ILD and IPF share similarities in how the underlying lung scarring, or fibrosis, forms in people with the disease, we are evaluating whether nintedanib can have a beneficial impact on lung fibrosis associated with SSc, said Dr William Mezzanotte, Therapeutic Area Head, Respiratory Medicine at Boehringer Ingelheim.
Because SSc-ILD and IPF share similarities in how the underlying lung scarring, or fibrosis, forms in people with the disease, we are evaluating the impact of nintedanib on lung fibrosis associated with systemic sclerosis," said Danny McBryan, M.
In conclusion, YTE could ameliorate BLM-induced lung fibrosis by alleviating HMGB1 activity and TGF-[beta]1 activation, suggesting therapeutic potential for PF.
11 patient organisations including AMA Fuori dal Buio, Belgische vereniging voor longfibrose, British Lung Foundation, Association pour la fibrose pulmonaire idiopathique, Irish Lung Fibrosis Association, Action for Pulmonary Fibrosis, Asociacion de Familiares y Enfermos de Fibrosis Pulmonar Idiopatica, Lungenfibrose, Longfibrose Patientenvereniging, LOT Austria, Long Fonds.
The procedure is approved for people with symptomatic aortic stenosis who are considered a high risk patient for standard valve replacement surgery", he said, also citing the elderly as well as patients suffering from kidney failure and lung fibrosis.
They also found that when they treated the mice with a new experimental drug designed to block alpha v integrins, the animals were protected from liver and lung fibrosis.
He was diagnosed with lung fibrosis in 2010 and is survived by wife Judith, a daughter and two sons.
Terence Moran, chairman of the Irish Lung Fibrosis Association, (ILFA), said: "Our members and other patients living
Lorna Murphy, of the Irish Lung Fibrosis Association, said: "This is the first and only drug available to treat this disease.
Circulating Thought to be progenitors for fibroblasts fibrocytes participating in the pathogenesis of lung fibrosis.
Two case series explore common complications of advanced HIV disease, including CMV retinitis (Laher), suggesting reasonable outcomes despite the absence of systemic therapy, and Pneumocystis pneumonia (Shaddock), providing evidence for lung fibrosis in individuals with advanced disease requiring ventilation.