antiinflammatory drug

(redirected from Loteprednol Etabonate)
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antiinflammatory drug 

A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.
References in periodicals archive ?
In the four-arm study, 514 patients undergoing cataract surgery at 47 clinical sites across the US were randomised to receive either sub-micron loteprednol etabonate ophthalmic gel (0.
According to the company, the new gel formulation features a sub-micron particle size to enhance tissue penetration of the drug and a lower concentration of loteprednol etabonate (0.
Prednisolone acetate 1% was discontinued and loteprednol etabonate 0.