losartan
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Related to losartan: losartan potassium, losartan-hydrochlorothiazide
losartan
[lo-sahr´tan]an angiotensin II receptor antagonist used as an antihypertensive; used as the potassium salt.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
losartan
(lō-sär′tăn)n.
An angiotensin II receptor blocker drug, C22H23ClN6O, used in the form of its potassium salt to treat hypertension.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
losartan
Cozaar® Pharmacology A sartan which blocks angiotensin II–A-II from binding to AT1, ↓ proteinuria and filtration fraction, inhibits secretion of aldosterone by the adrenal cortex, and ↑ uric acid excretion; in Pts with CHF, losartan ↓ afterload, ↑ cardiac output–effects shared by ACE inhibitors—and prevent left ventricular hypertrophy Side effects Vertigo. See Angiotensin II receptor antagonist, ELITE.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
losartan
An angiotensin II antagonist drug used to treat high blood pressure (HYPERTENSION). In the LIFE trial of this drug, reported on in 2003, a subgroup of diabetic patients taking the drug showed a 37 percent reduction in mortality from heart attacks or strokes and a 39 percent reduction in overall mortality over people on other treatment. The drug appears to be effective in preventing sudden death from heart arrhythmias. A brand name is Cozaar. The drug is available combined with the diuretic drug HYDROCHLOROTHIAZIDE under the brand name Cozaar-Comp.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005