double dagger]) Per 10% increase in cephalosporin prescribing during the previous year; includes cefaclor, cefadroxil, cefdinir, cefditoren pivoxil, cefixime, cefpodoxime proxetil, cefprozil, ceftibuten, cefuroxime axetil, cephalexin, cephradine, and loracarbef
21] Cefaclor, cefixime and loracarbef
are less active in vitro against S.
cancerogenus has a natural resistance to amoxicillin, amoxicillin/clavulanic acid, cefazolin, cefaclor, cefazoline, loracarbef
, and cefloxitin.
06 [micro]g/ml can be considered susceptible to amoxicillin, amoxicillin-clavulanic acid, cefaclor, loracarbef
, cefprozil, cefuroxime and cefpodoxime for approved indications.
Antimicrobial drug suspensions: a blinded comparison of taste of twelve common pediatric drugs including cefixime, cefpodoxime, cefprozil and loracarbef
Also not listed are cefaclor and loracarbef
because their efficacy, by current standards, has not been tested and they are anticipated not to be that good, although the tolerability is excellent.
Amoxicillin 01 Amoxicillin and Clavulanic Acid (Augmentin) 02 Azithromycin (Zithromax) 03 Cafaclor (Ceclor) 04 Cefixime (Suprax) 05 Cefpodoxime (Vantin) 06 Cefprozil (Cefzil) 07 Cetriaxone (Rocephin) 08 Clarithromycin (Biaxin) 09 Erythromycin and Sulfisoxazone (Pediazole) 10 Loracarbef
(Lorabid) 11 Trimethoprim and Sulfamethoxazole (Bactrim, Septra) 12 Other 13 No Data 99
Other effective agents include clarithromycin, cefprozil, loracarbef
, and amoxicillin and clavulanic acid.
In Enterobacter cancerogenus, resistance to amoxicillin, amoxicillin/clavulanic acid, cefazolin, cefaclor, cefazoline, loracarbef
, and cefloxitin may indicate the presence of
TABLE 4 Compliance-Enhancing Ranking of Antibiotic Suspensions STRONGLY COMPLIANCE-ENHANCING * Amoxicillin * Cefdinir (Omnicef) * Loracarbef
(Lorabid) * Cefaclor (Ceclor) * Cefixime (Suprax) MODERATELY COMPLIANCE-ENHANCING * Cefprozil (Cefzil) * Ceftibuten (Cedax) EQUIVOCAL COMPLIANCE-ENHANCING * Azithromycin (Zithromax) NOT COMPLIANCE-ENHANCING * Amoxicillin-clavulanate (Augmentin) * Erythromycin-sulfasoxazole (Pediazole) * TMP-SMX (Bactrim or Septra) DISCOURAGES COMPLIANCE * Cefpodoxime (Vantin) * Cefuroxime (Ceftin) * Clarithromycin (Biaxin) TMP-SMX, trimethoprim sulfamethoxazole Sources: Adapted from Steele RW, et al.
Antibiotic susceptibility of upper respiratory tract pathogens in Sweden: a seven year follow-up study including loracarbef
A total of 4,782 children were randomized to treatment with 10 days of penicillin, or 5 days of amoxicillin and potassium clavulanate (Augmentin), ceftibuten (Cedax), cefuroxime axetil (Ceftin), loracarbef
(Lorabid), clarithromycin (Biaxin), or erythromycin.