London Criteria

London Criteria

The criteria for defining myalgic encephalomyelitis/post-viral fatigue syndrome (ME/PVFS).

Diagnostic criteria for ME/PVFS research subjects
(a) Exercise-induced fatigue precipitated by minimal exertion relative to patient's previous exercise tolerance.
(b) Impairment of short-term memory—loss of concentration, usually coupled with other neurologic and psychological disturbances such as emotional lability, nominal dysphasia, disturbed sleep patterns, disequilibrium or tinnitus.
(c) Fluctuation of symptoms, usually precipitated by either physical or mental exercise, (b) above.

These symptoms should have been present for at least 6 months and should be ongoing.
References in periodicals archive ?
The London criteria include (a) exercise-induced fatigue caused by small amounts of exertion (physical or mental) compared to previously tolerated levels, (b) neurological disturbances, especially impaired memory and concentration, (c) fluctuation of symptoms, and (d) the requirement for the ongoing presence of these symptoms for at least 6 months (National Task Force, 1994).
Patients with ME were diagnosed according to the London criteria (National Task Force, 1994).
A total of 26 patients (19 females: 73% and 7 males: 27%) met the London criteria for ME (National Task Force, 1994).
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