Löfgren's syndrome

(redirected from Lofgren syndrome)

Löfgren’s syndrome

(lĕf′grĕnz, löf′)
[Sven Löfgren, Swedish physician, 1910–1978]
A type of sarcoidosis characterized by extensive involvement of hilar lymph nodes, erythema nodosum, and joint pains, esp. around the ankles. The syndrome has a better prognosis than other forms of sarcoidosis.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Acute arthritis occurs in up to 40% patients with sarcoidosis and can be the presenting manifestation, usually as a part of Lofgren syndrome (a triad of acute arthritis, bilateral hilar adenopathy, and erythema nodosum) (1, 2, 5).
Stankovic et al., "Lofgren syndrome and peritoneal involvement by sarcoidosis: Case report," CHEST, vol.
Her EN and joint pain were concerning for an autoimmune process, particularly acute sarcoidosis (Lofgren syndrome); therefore antibiotics were discontinued and she was started on ibuprofen 800 mg every 8 hours.
At this point, acute sarcoidosis (Lofgren syndrome) was ruled out.
The majority of cases (5/6) were pulmonary with mainly hilar and/or mediastinal adenopathies; one male patient had Lofgren syndrome.
In fact, other authors concluded that there was no clinical difference between familial sarcoidosis and usual forms of the disease (13), only Lofgren syndrome stood out (14).In our case, the relationship is a brother to brother matter.
In studies investigating the association between non-HLA genes and sarcoidosis (Table 2), TNF-308A allele gene polymorphism was detected to be correlated with Lofgren syndrome (9).