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a bacterial species that causes diphtheria and produces a powerful exotoxin causing degeneration of various tissues, notably myocardium, in humans and experimental animals, and catalyzing the ADP-ribosylation of elongation factor II; virulent strains of this organism are lysogenic; it is commonly found in membranes in the pharynx, larynx, trachea, and nose in cases of diphtheria; it is also found in apparently healthy pharynx and nose in carriers, and occasionally in the conjunctiva and in superficial wounds; it occasionally infects the nasal passages and wounds of horses; it is the type species of the genus Corynebacterium.
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[Friedrich August Johannes Loeffler (Löffler), Ger. bacteriologist, 1852–1915]Corynebacterium diphtheriae.
Medical Dictionary, © 2009 Farlex and Partners
Loeffler,(Löffler), Friedrich A.J., German bacteriologist and surgeon, 1852-1915.
Klebs-Loeffler bacillus - see under Klebs
Loeffler bacillus - a species that causes diphtheria. Synonym(s): Corynebacterium diphtheriae
Loeffler blood culture medium - a culture medium for the isolation of Corynebacterium diphtheriae.
Loeffler caustic stain - a stain for flagella, utilizing an aqueous solution of tannin and ferrous sulfate with the addition of an alcoholic fuchsin stain.
Loeffler methylene blue - a stain for diphtheria organisms.
Loeffler stain - a stain for flagella.
Medical Eponyms © Farlex 2012