Loeffler's syndrome


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Loeffler's syndrome

Acute Pulmonary Eosinophilia

A self-limiting non-infectious inflammation in the lungs accompanied by increased eosinophils in tissue and peripheral blood.
Aetiology Unknown, or various drugs, parasitic infestation (especially ascariasis in children), nickel exposure, recent blood transfusion, or lymphangiography.
Clinical findings Chest pain, dry cough, fever, malaise, tachypnoea, dyspnoea, rash, wheezing.
Imaging Diffuse infiltrates on plain AP film.
Bronchoscopy Increased eosinophils.
Management APE may respond to corticosteroids.
Complications Restrictive cardiomyopathy due to pericardial fibrosis
Prognosis Often resolves without therapy; less commonly, it evolves to acute idiopathic eosinophilic pneumonia.

Loeffler's syndrome

A form of patchy pneumonia featuring fever, cough, difficulty in breathing, associated with a marked rise in the numbers of EOSINOPHIL white cells in the lungs and the circulating blood. (Wilhelm Loeffler, Swiss physician, b. 1887).

Loeffler's syndrome

The respiratory phase of ascariasis, marked by inflammation of the lungs and eosinophilia.
Mentioned in: Roundworm Infections