Locus ceruleus


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Related to Locus ceruleus: Raphe nuclei

locus

 [lo´kus] (L.)
1. a place or site.
2. in genetics, the specific site of a gene on a chromosome.
locus ceru´leus a pigmented eminence in the superior angle of the floor of the fourth ventricle of the brain.
locus of control a belief regarding responsibility for actions. Individuals with an internal locus of control generally hold themselves responsible for actions and consequences, while those with an external locus of control tend to believe that they are not able to affect a personal outcome and that luck or destiny are responsible for their actions.

Locus ceruleus

Brain region that processes sensory signals from all areas of the body.
References in periodicals archive ?
Curtis et al., "Presynaptic inhibition of diverse afferents to the locus ceruleus by K-opiate receptors: a novel mechanism for regulating the central norepinephrine system," Journal of Neuroscience, vol.
The activity of the noradrenergic neurons is decreased by agonists acting at [alpha]2-adrenergic receptors on the locus ceruleus cell bodies.
Adicionalmente, se ha observado que los pacientes con parkinsonismo padecen de degeneraciones en nucleos subcorticales en el area ventral-tegmental, hipotalamo, nucleo dorsal del rafe y locus ceruleus. Estas degeneraciones han sido observadas tambien en pacientes con depresion (Lieberman, 2006; McDonald et al., 2003).
Hypocretinergic neurons also send projections into brainstem areas that control various aspects of wake and rapid eye movement (REM) sleep (the locus ceruleus, raphe nuclei and reticular formation).
The chemical signals initiating the different aspects of the stress response are triggered by two factors in the brain, says Gold: corticotropin-releasing hormone (CRH) and a bundle of neurons called the locus ceruleus. Actions of both are strongly implicated also in melancholic depression, he says.
Naghdi, "Effect of reversible inactivation of locus ceruleus on spatial reference and working memory," Neuroscience, vol.
The locus ceruleus norepinephrine system: functional organization and potential clinical significance.
The sedation effect of alpha 2 agonist is postulated to be in the locus ceruleus (a bilateral nucleus that contains many adrenergic receptors) in the brainstem.
A brain region that plays a role in muscle atonia, as well as in sleep, wake and the transitions between various sleep stages, is the locus ceruleus (LC), a blue-tinged area located in the rear upper brainstem.
Many patients with chronic daily headache are thought to have a down regulation of norepinephrine receptors caused by excessive release of norepinephrine from the locus ceruleus.