LAMA3

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LAMA3

A gene on chromosome 18q11.2 that encodes laminin alpha 3, an extracellular matrix subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta and gamma) involved in cell adhesion, signal transduction and keratinocyte differentiation.

Molecular pathology
LAMA3 mutations are associated with junctional epidermolysis bullosa (Herlitz type).
References in periodicals archive ?
Emerging Technologies in Lab-on-a-Chip: Microfluidics and uTAS is part of the semiconductor vertical subscription service, and examines the latest advances in microfluidic and uTAS LOC technologies that are likely to enable LOCs to move from the laboratory into the commercial world.
Other advantages of portability, rapid assay times, and smaller sample requirements are likely to accelerate the adoption of LOC technology, especially in the defense and public health sectors.
The prolific growth of plastics/polymers along with technological advances in microelectromechanical systems (MEMS), semiconductor microfabrication methods, biosensors, and biomedical engineering expects to have a positive impact on the commercialization of LOC.
However, many LOC researchers have lost sight of the bigger picture and actual market needs due to their constant bid to improve the design mechanics for microfluidics and uTAS.
Hence, the market for LOC microfluidic systems is likely to be limited, unless the technology demonstrates sufficient benefits to justify the additional investment.
The bonds of each series are subject to mandatory tender: (i) on interest mode conversion dates; (ii) on the day following the last day of each flexible interest rate period; and (iii) upon the expiration, termination or substitution of the LOC or SBPA relating to a series of bonds.
Positive, with the LOC provided by Fleet National Bank (rated
50 million subseries H-7 rated 'AA+/F1+' with the LOC provided
100 million subseries H-8 rated 'AAA/F1+' with the LOC
The above ratings are based on Fitch's new methodology that considers the joint probability of the failure of both a municipal issuer and a bank LOC provider.