loco

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loco

(lō′kō)
n. pl. lo·cos
1. See locoweed.
2. See locoism.
tr.v. lo·coed, lo·coing, lo·cos
1. To poison with locoweed.
2. Slang To cause to be mentally deranged; craze.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
References in periodicals archive ?
LOCAs were designated by team leaders in consultation with fieldwalkers, geomorphologists, processing team members, and other experts.
Despite the occasional flying saucer and demon billionaire, the only real unreality of Locas is that AIDS is barely mentioned.