local anesthetics


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lo·cal an·es·thet·ics

drugs used for the interruption of the nerve transmission of pain sensations. They act at the site of application to prevent perception of pain; examples include procaine and lidocaine.

lo·cal an·es·thet·ics

(lōkăl anĕs-thetiks)
Drugs used for the interruption of the nerve transmission of pain sensations; act at site of application to prevent perception of pain.
References in periodicals archive ?
Allergic reactions to local anesthetics in dental patients: Analysis of intracutaneous and challenge tests.
However, in the literature, the development of methemoglobinemia has also been reported after topical use of local anesthetics at therapeutic doses, as in our patients (12,13).
However, patients with allergy to local anesthetic agents, need multiple teeth, or surgical extraction were excluded.
After local anesthetic administration peripheral blood glucose estimation was repeated after 10 minutes and 20 minutes.
Seventy-six percent of the participants used local anesthetics every day or more than twice a week, though 56.7% of them stated that they had not received any training in the use of local anesthetics during their education.
Specifically, studies have shown a local anesthetic sparing effect, shorter duration of labor, and improvements in maternal satisfaction with PIEB compared to CEI (9).
Ultrasound guidance unequivocally decreases the incidence of local anesthetic systemic toxicity [26].
[18], whereas the needle positioning was accomplished under ultrasound guidance using a subsartorial approach with the visible local anesthetic spread around the femoral artery.
Local anesthetic infiltration was applied two minutes before epidural needle insertion.
Topical anesthetic application, such asEMLA (Eutectic mixture of local anesthetics:lidocaine 2.5%-prilocaine 2.5%) creamapplied 60 to 120 minutes prior to intralesionalanesthetic injection has been found in multiple studies to attenuate injection pain.17 Similarly,LET solution (lidocaine, epinephrine, tetracaine) application 30 minutes before wound/laceration closure,prior to actual lidocaine infiltration has been found to decrease the pain.18The disadvantage with these techniques is the extra time required for EMLA or LET to show the effect.
Mulroy and other investigators have now reported the significant impact of the route of administration of local anesthetics on an increasing prevalence rates of local anesthetic systemic toxicity reactions.11-14 The prevalence of local anesthetic systemic toxicity in epidural anesthetics ranged from 1.
With the least suspicion of an effect on the patient, the perfusion of local anesthetics should be withdrawn, and close monitoring of the maternal-fetal state should be performed.

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