In order to increase the duration of block, Dexmedetomidine has been used as an adjuvant to local anaesthetics
in different regional techniques.
The introduction of cocaine in 1884 as a local anaesthetic
agent started an entire new era in medicine.
In a recent experimental study, investigators from Uludag University School of Medicine, Bursa, Turkey investigated the possible therapeutic effects of local anaesthetics
, from lidocaine to the more recent ropivacaine, have been used as pre-emptive analgesics since the 1980s.
Moreover, it does not seem to produce clinically relevant differences compared with stimulating and injecting only at the tibial branch when injecting high volumes of local anaesthetic
The use of a local anaesthetic
as either a bolus injection or a continuous infusion into the paravertebral space to provide analgesia is a long established technique.
Chirocaine is the trade name for levobupivacaine, the long-acting local anaesthetic
developed by Chiroscience for use in a wide range of surgical procedures, as well as in pain relief during childbirth and in pain management following surgery.
It also improves the quality and duration of analgesia over local anaesthetics
Nevertheless, researchers concluded that local anaesthetics
might have potential therapeutic effects on IBD based on their findings.
The aim of this study was to determine and compare the MICs of local anaesthetics
and additives commonly used in epidural infusions, against organisms implicated in the formation of epidural abscesses.
Injecting 1 ml of local anaesthetic
should abolish the twitch.
Ghaderi et al found in their study that cooling the injection site before infiltration of local anaesthetics
for 1 min, reduces the pain perceived by pediatric patients.