16) Similar to classic LCIS, pleomorphic LCIS fills and distends lobules
in a loosely cohesive manner, but it also tends to show a florid growth pattern (described below) and is frequently associated with central, comedo-type necrosis and calcifications (Figure 2, A through C).
The membrane was composed of the surface serosa and deep connective tissue, while the parenchyma was composed of the hepatic lobule
and portal area (Figs.
The protrusion of the ear is measured on an imaginary plane extending from the helical margin to the scalp, which typically projects laterally by 10 to 12 mm at the upper pole, by 16 to 18 mm at midpoint, and by 20 to 22 mm at the lobule
The susceptibility window--when potentially cancer-causing mutations can collect in vulnerable breast lobule
cells--only closes when a woman has her first full-term pregnancy.
a) Area of heavily pigmented dark brown tumor lobules
and (b) tumor lobules
Paraffin embedded tissues were stained with Periodic acid Schiff (PAS) and haematoxylin to observe the glycogen content of the hepatocytes,17 depending upon the distribution of glycogen containing hepatocytes in a lobule
and graded on the basis of zonal distribution.
13-15 Widespread degenerative changes varying from ballooning of cell to necrosis and accumulation of mononuclear cells in hepatic lobules
were observed in fluoride toxicity.
Our results revealed testicular lobules
of variable shapes and sizes according to seasons, where it decreased in size during winter which was cold, rainy and short day light season (resting season) and thereafter increased during spring and reached a maximum size during summer which was hot, dry and long day light season (spawning season) as they were distended by different developmental stages of spermatogenic cells and they showed slight decrease again during autumn which was dry and less hot than spawning season (spent season) but still enlarged and larger as compared to structure during winter.
These liver sections provided well-marked liver lobules
for the analysis--vide supra.
However, by the end of pregnancy, 85% of breast tissue has matured into cancer-resistant Type 4 lobules
because of hormones made by the fetal-placenta unit.
Microscopically the tissue composed of lobules
of fibro-connective elements with abundant myxoid stroma, dystrophic calcification with scattered hemosiderin-laden macrophages, multinucleated giant cells and occasional squamous cells.
This type of breast cancer develops in the lobules
, which are the milk-producing parts of the breast.