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A chronic localized mycosis of the skin reported from South America resulting in granulomatous nodules or keloids that contain budding, thick-walled cells about 9 mcm in diameter, that is, the tissue form of Loboa loboi, the causative fungus, which has not been cultured. Also occurs in dolphins.
Synonym(s): Lobo disease
Farlex Partner Medical Dictionary © Farlex 2012


(lo?bo-mi-ko'sis) [ (Lacazia) loboi + mycosis]
A fungal infection of the cutaneous and subcutaneous tissues in which nodules resembling keloids, plaques, or warts form on the skin, caused by Lacazia loboi. Treatment is surgical. Synonym: keloidal blastomycosisLobo disease
Medical Dictionary, © 2009 Farlex and Partners


Jorge, Brazilian physician, 1900-1979.
Lobo disease - a chronic localized mycosis of the skin. Synonym(s): lobomycosis
lobomycosis - Synonym(s): Lobo disease
Medical Eponyms © Farlex 2012
References in periodicals archive ?
Ten years experience with Jorge Lobo's disease in the state of Acre, Amazon region, Brazil.
Natural history of Jorge Lobo's disease. Ocurrence among Indians Caiabi (central Brazil) [in Portuguese].
A possible case of Lobo's disease acquired in Europe from a bottle-nosed dolphin (Tursiops truncatus).
Jorge Lobo's disease: a case of keloidal blastomycosis (lobomycosis) in a nonendemic area.
Disease that shows keloidal-like granulomas in humans and dolphins has been known by several different names, such as Jorge Lobo disease (4), Lobo's disease (3,5,22), lobomycosis (1,6,13,16,19,23,24), and lacaziosis (11,12,14,15).
A case of Lobo's disease in the dolphin Sotalia guianesis.
Lobo's disease in an Atlantic bottle-nosed dolphin.
Lobo's disease in a bottlenose dolphin (Tursiops truncatus) from Matagorda Bay, Texas.
A second human case was reported in 1938, after which the disease was termed Lobo's disease (2).
In 1973, a dolphin with Lobo's disease was described in Europe along the Atlantic coast of France and Spain (11).
One dolphin with Lobo's disease was successfully treated with miconzaole (2).
Early diagnosis and prompt treatment by surgery in Jorge Lobo's disease (keloidal blastomycosis).