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A chronic localized mycosis of the skin reported from South America resulting in granulomatous nodules or keloids that contain budding, thick-walled cells about 9 mcm in diameter, that is, the tissue form of Loboa loboi, the causative fungus, which has not been cultured. Also occurs in dolphins.
Synonym(s): Lobo disease


(lo?bo-mi-ko'sis) [ (Lacazia) loboi + mycosis]
A fungal infection of the cutaneous and subcutaneous tissues in which nodules resembling keloids, plaques, or warts form on the skin, caused by Lacazia loboi. Treatment is surgical. Synonym: keloidal blastomycosisLobo disease


Jorge, Brazilian physician, 1900-1979.
Lobo disease - a chronic localized mycosis of the skin. Synonym(s): lobomycosis
lobomycosis - Synonym(s): Lobo disease


a skin disease of dolphins caused by the yeast loboa loboi and manifested by dermal granulomas or keloids, especially around the head. The disease is a debilitating one and may kill the dolphin.
References in periodicals archive ?
Disease that shows keloidal-like granulomas in humans and dolphins has been known by several different names, such as Jorge Lobo disease (4), Lobo's disease (3,5,22), lobomycosis (1,6,13,16,19,23,24), and lacaziosis (11,12,14,15).
A case of Lobo's disease in the dolphin Sotalia guianesis.
Lobo's disease in an Atlantic bottle-nosed dolphin.
A possible case of Lobo's disease acquired in Europe from a bottle-nosed dolphin (Tursiops truncatus).
Ten years experience with Jorge Lobo's disease in the state of Acre, Amazon region, Brazil.
Lobo's disease in a bottlenose dolphin (Tursiops truncatus) from Matagorda Bay, Texas.
A second human case was reported in 1938, after which the disease was termed Lobo's disease (2).
In 1973, a dolphin with Lobo's disease was described in Europe along the Atlantic coast of France and Spain (11).
One dolphin with Lobo's disease was successfully treated with miconzaole (2).